The uptake of nucleosides (or nucleobases) is essential for nucleic acid synthesis in many
human cell types and in parasitic organisms that cannot synthesize nucleotides de novo …

Nucleoside transporters mediate cellular uptake of physiologic nucleosides for nucleic acid
synthesis in the salvage pathways in many cell types. These transporters also play an …

Nucleoside transporters play a critical role in the absorption, disposition, and targeting of
therapeutically used nucleosides and nucleoside analogs. This review is focused on the …

Nucleoside analogues used in cancer and anti-viral therapies interfere with nucleotide
metabolism and DNA replication, thus inducing their pharmacological effects. A long …

Most mammalian cells possess nucleoside transporters that mediate the cellular uptake of
physiologic purine and pyrimidine nucleosides for incorporation into cellular nucleotides …

Hydrophilic purine and pyrimidine nucleosides rely on specialized carrier proteins for their
membrane translocation. The recent identification of two gene families encoding …

Pyrimidine and purine nucleosides and their derivatives have critical functions and
pharmacological applications in the brain. Nucleosides and nucleobases are precursors of …

Nucleoside analogs are important components of treatment regimens for various
malignancies. Nucleoside-specific membrane transporters mediate plasma membrane …

Nucleoside transporters (NT) facilitate the movement of nucleosides and nucleobases
across cell membranes. NT-mediated transport is vital for the synthesis of nucleic acids in …

Nucleoside transporters (NT) are integral membrane proteins implicated in the salvage of
natural nucleobases and nucleosides for nucleic acid synthesis. These proteins also play a …