Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

Langerhans cell histiocytosis is a disorder characterized by lesions that include CD207+
dendritic cells along with an inflammatory infiltrate. Langerhans cell histiocytosis has a …

Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the
accumulation of CD 1a+/Langerin+ LCH cells and wide‐ranging organ involvement …

More than a century after its first description, Langerhans cell histiocytosis (LCH) still
remains an intriguing disease. Considerable progress in understanding its biology has been …

Abstract “Langerhans cell histiocytosis”(LCH) describes a spectrum of clinical presentations
ranging from a single bone lesion or trivial skin rash to an explosive disseminated disease …

Background Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown
etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone …

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of cells with the
phenotype of activated Langerhans cells. The diagnosis of LCH is often delayed or missed …

Treatment of Langerhans cell histiocytosis (LCH) over the past 50 years has reflected the
changing concepts of the disease process. Fifty years ago the disease was thought to be of …

Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of
clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary …

Adult Langerhans cell histiocytosis (LCH) remains poorly defined. We retrospectively
studied 266 newly diagnosed LCH patients to understand the clinical presentation …