Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese …

S Bhasin, M Pencina, GK Jasuja… - The Journal of …, 2011 - academic.oup.com
Context: Reference ranges are essential for partitioning testosterone levels into low or
normal and making the diagnosis of androgen deficiency. We established reference ranges …

Harmonized reference ranges for circulating testosterone levels in men of four cohort studies in the United States and Europe

TG Travison, HW Vesper, E Orwoll, F Wu… - The Journal of …, 2017 - academic.oup.com
Background: Reference ranges for testosterone are essential for making a diagnosis of
hypogonadism in men. Objective: To establish harmonized reference ranges for total …

A population-level decline in serum testosterone levels in American men

TG Travison, AB Araujo, AB O'Donnell… - The Journal of …, 2007 - academic.oup.com
Context: Age-specific estimates of mean testosterone (T) concentrations appear to vary by
year of observation and by birth cohort, and estimates of longitudinal declines in T typically …

Measurement of Total Serum Testosterone in Adult Men: Comparison of Current Laboratory Methods Versus Liquid Chromatography-Tandem Mass Spectrometry

C Wang, DH Catlin, LM Demers… - The Journal of …, 2004 - academic.oup.com
The diagnosis of male hypogonadism requires the demonstration of a low serum
testosterone (T) level. We examined serum T levels in pedigreed samples taken from 62 …

Decline in serum testosterone levels among adolescent and young adult men in the USA

SD Lokeshwar, P Patel, RJ Fantus, J Halpern… - European urology …, 2021 - Elsevier
Testosterone deficiency has a prevalence of 20% among adolescent and young adult (AYA)
males. Although previous studies have shown that total testosterone (TT) levels are …

Reference ranges and determinants of testosterone, dihydrotestosterone, and estradiol levels measured using liquid chromatography-tandem mass spectrometry in a …

BB Yeap, H Alfonso, SAP Chubb… - The Journal of …, 2012 - academic.oup.com
Context: Testosterone (T) levels decline with increasing age. Controversy exists over the
threshold for classifying T as low vs. normal in older men. The relevance of assessing …

Low free testosterone is associated with hypogonadal signs and symptoms in men with normal total testosterone

L Antonio, FCW Wu, TW O'Neill, SR Pye… - The Journal of …, 2016 - academic.oup.com
Context: During aging, total testosterone (TT) declines and SHBG increases, resulting in a
greater decrease in calculated free T (cFT). Currently, guidelines suggest using TT to …

Normal, bound and nonbound testosterone levels in normally ageing men: results from the Massachusetts Male Ageing Study

BA Mohr, AT Guay, AB O'Donnell… - Clinical …, 2005 - Wiley Online Library
Objective There is little consensus on what androgen levels are 'normal'for healthy, ageing
men. Using data from the Massachusetts Male Ageing Study (MMAS), we estimated age …

Testosterone concentrations in diabetic and nondiabetic obese men

S Dhindsa, MG Miller, CL McWhirter, DE Mager… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To determine the prevalence of subnormal testosterone concentrations in
patients with obesity and with type 2 diabetes in a primary care clinic population …

Standardization of testosterone measurements in humans

HW Vesper, JC Botelho - The Journal of steroid biochemistry and …, 2010 - Elsevier
Testosterone levels are used primarily for the diagnosis of hypogonadism in men and
androgen excess in women. Current studies suggest that serum testosterone measurements …