Traumatic brain injury (TBI) is a risk factor for dementia. Mixed neurodegenerative
pathologies have been described in late survivors of TBI, but the mechanisms driving post …

Background Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which
typically develops within 2 years post-injury with poorly understood mechanisms. We …

Traumatic brain injury (TBI) is the leading cause of death in young adults and children. The
treatment of TBI in the acute phase has improved substantially; however, the prevention and …

Although concussion is now recognized as a major health issue, its non-lethal nature has
limited characterization of the underlying pathophysiology. In particular, potential …

The blood-brain barrier (BBB) is a complex and dynamic physiological interface between
brain parenchyma and cerebral vasculature. It is composed of closely interacting cells and …

Our understanding of BBB breakdown acutely after the cerebrovascular injury has come a
long way; however, we lack a clear understanding of the course of BBB disruption and BBB …

Clinical studies suggest that traumatic brain injury (TBI) hastens cognitive decline and
development of neuropathology resembling brain aging. Blood–brain barrier (BBB) …

The blood–brain barrier (BBB) is an anatomical microstructural unit, with several different
components playing key roles in normal brain physiological regulation. Formed by tightly …

The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial
cells, but its normal function also depends on paracrine interactions between the brain …

Traumatic brain injuries (TBIs) account for the majority of injury-related deaths in the United
States with roughly two million TBIs occurring annually. Due to the spectrum of severity and …