Vitamin C intervention for critical COVID-19: A pragmatic review of the current level of evidence

P Holford, AC Carr, M Zawari, MP Vizcaychipi - Life, 2021 - mdpi.com
Severe respiratory infections are characterized by elevated inflammation and generation of
reactive oxygen species (ROS) which may lead to a decrease in antioxidants such as …

Vitamin C supplementation for the treatment of COVID-19: a systematic review and meta-analysis

M Olczak-Pruc, D Swieczkowski, JR Ladny, M Pruc… - Nutrients, 2022 - mdpi.com
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, caused by the
severe respiratory syndrome coronavirus 2 (SARS-CoV-2), millions of people have died …

Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis

L Sun, JH Zhao, WY Fan, B Feng, WW Liu… - Nutrition …, 2023 - academic.oup.com
Abstract Context Coronavirus disease 2019 (COVID-19) could induce the “cytokine storm”
due to overactivation of immune system and accompanied by acute respiratory distress …

[HTML][HTML] The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study

D Gao, M Xu, G Wang, J Lv, X Ma, Y Guo… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: The inflammatory reaction is the main cause of acute respiratory distress
syndrome and multiple organ failure in patients with Coronavirus disease 2019, especially …

The emerging role of vitamin C in the prevention and treatment of COVID-19

AC Carr, S Rowe - Nutrients, 2020 - mdpi.com
Investigation into the role of vitamin C in the prevention and treatment of pneumonia and
sepsis has been underway for many decades. This research has laid a strong foundation for …

Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials

D Rawat, A Roy, S Maitra, A Gulati, P Khanna… - Diabetes & Metabolic …, 2021 - Elsevier
Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …

[HTML][HTML] Role of vitamin C in preventing of COVID-19 infection, progression and severity

U Shahbaz, N Fatima, S Basharat, A Bibi, X Yu… - AIMS …, 2022 - ncbi.nlm.nih.gov
Vitamin C stands as an essential water-soluble vitamin, antioxidant and has been shown to
enhance immunity. SARS-CoV-2 has been spreading rapidly across the worldwide, several …

Vitamin C in the Treatment of COVID-19

GP Milani, M Macchi, A Guz-Mark - Nutrients, 2021 - mdpi.com
Vitamin C is an essential nutrient that serves as antioxidant and plays a major role as co-
factor and modulator of various pathways of the immune system. Its therapeutic effect during …

The effect of vitamin C on the risk of mortality in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials

CS Kow, SS Hasan, DS Ramachandram - Inflammopharmacology, 2023 - Springer
Abstract Background and Aims Vitamin C appears to be a viable treatment option for
patients with COVID-19. Methods We conducted a systematic review and meta-analysis of …

Vitamin C—An adjunctive therapy for respiratory infection, sepsis and COVID-19

P Holford, AC Carr, TH Jovic, SR Ali, IS Whitaker… - Nutrients, 2020 - mdpi.com
There are limited proven therapies for COVID-19. Vitamin C's antioxidant, anti-inflammatory
and immunomodulating effects make it a potential therapeutic candidate, both for the …