Research advances in the role of blood metabolic markers in the treatment response and prognosis prediction of primary liver cancer

LIU Zhiying, Z Zhihang, HE Song - 临床肝胆病杂志, 2023 - lcgdbzz.org
Primary liver cancer is one of the most severe cancer burdens around the world. Metabolic
reprogramming is one phenotype of cancer, and blood metabolic markers are closely …

Research advances in metabolic markers for hepatocellular carcinoma

S WenBo, L Wei - 临床肝胆病杂志, 2018 - lcgdbzz.org
Hepatocellular carcinoma (HCC) has high incidence and mortality rates and poor prognosis
and greatly threatens human health. Early identification and diagnosis is an important …

Cancer metabolism: a novel perspective on precision diagnosis and treatment for liver cancer

Z Ning, G Tan - Zhonghua wai ke za zhi [Chinese Journal of Surgery …, 2020 - europepmc.org
Metabolic reprogramming has been identified as a hallmark of cancer. Liver is an essential
hub in the body for the metabolism of three major nutrients including glucose, lipids and …

Metabolomics in hepatocellular carcinoma: From biomarker discovery to precision medicine

X Wu, Z Wang, L Luo, D Shu, K Wang - Frontiers in Medical …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) remains a global health burden, and is mostly diagnosed
at late and advanced stages. Currently, limited and insensitive diagnostic modalities …

Dysregulated serum metabolites in staging of hepatocellular carcinoma

W Wang, J Lv, N Chen, B Lou, W Mao, P Wang… - Clinical …, 2018 - Elsevier
Background Correct staging of hepatocellular carcinoma (HCC) could help physicians to
precisely select treatments for patients, such as surgery, chemotherapy, or their combination …

Tumor metabolism and associated serum metabolites define prognostic subtypes of Asian hepatocellular carcinoma

Y Pomyen, A Budhu, J Chaisaingmongkol… - Scientific Reports, 2021 - nature.com
Abstract Treatment effectiveness in hepatocellular carcinoma (HCC) depends on early
detection and precision-medicine-based patient stratification for targeted therapies …

[HTML][HTML] Plasma metabolomic analysis of human hepatocellular carcinoma: diagnostic and therapeutic study

Y Chen, J Zhou, J Li, J Feng, Z Chen, X Wang - Oncotarget, 2016 - ncbi.nlm.nih.gov
Many hepatocellular carcinoma (HCC) patients suffer from late stages when diagnosed,
leading to dismal prospects for cure. Improving the diagnosis and treatment of HCC remains …

Prognosis prediction of hepatocellular carcinoma after surgical resection based on serum metabolic profiling from gas chromatography-mass spectrometry

C Fang, B Su, T Jiang, C Li, Y Tan, Q Wang… - Analytical and …, 2021 - Springer
Comprehensive prognostic risk prediction of hepatocellular carcinoma (HCC) after surgical
treatment is particularly important for guiding clinical decision-making and improving …

Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation

W Guo, HY Tan, N Wang, X Wang… - Cancer management and …, 2018 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the third most common cause of death from cancer, with
increasing prevalence worldwide. The mortality rate of HCC is similar to its incidence rate …

Serum metabolomics reveals the deregulation of fatty acids metabolism in hepatocellular carcinoma and chronic liver diseases

L Zhou, Q Wang, P Yin, W Xing, Z Wu, S Chen… - Analytical and …, 2012 - Springer
Patients with chronic liver diseases (CLD) including chronic hepatitis B and hepatic cirrhosis
(CIR) are the major high-risk population of hepatocellular carcinoma (HCC). The differential …