Genomic and structural mechanistic insight to reveal the differential infectivity of omicron and other variants of concern

P Sharma, M Kumar, MK Tripathi, D Gupta… - Computers in Biology …, 2022 - Elsevier
Background The genome of SARS-CoV-2, is mutating rapidly and continuously challenging
the management and preventive measures adopted and recommended by healthcare …

Divergent mutations of Delta and Omicron variants: key players behind differential viral attributes across the COVID-19 waves

A Panja, J Roy, A Mazumder, SM Choudhury - Virusdisease, 2023 - Springer
The third SARS-CoV-2 pandemic wave causing Omicron variant has comparatively higher
replication rate and transmissibility than the second wave-causing Delta variant. The exact …

Insights from a computational analysis of the SARS‐CoV‐2 Omicron variant: Host–pathogen interaction, pathogenicity, and possible drug therapeutics

MSA Parvez, MK Saha, M Ibrahim… - Immunity …, 2022 - Wiley Online Library
Introduction Prominently accountable for the upsurge of COVID‐19 cases as the world
attempts to recover from the previous two waves, Omicron has further threatened the …

In silico genome analysis reveals the evolution and potential impact of SARS-CoV-2 Omicron structural changes on host immune evasion and antiviral therapeutics

D Chauhan, N Chakravarty, AV Jeyachandran… - Viruses, 2022 - mdpi.com
New variants of SARS-CoV-2 continue to evolve. The novel SARS-CoV-2 variant of concern
(VOC) B. 1.1. 529 (Omicron) was particularly menacing due to the presence of numerous …

Computational investigation reveals that the mutant strains of SARS-CoV2 have differential structural and binding properties

R Kumar, R Kumar, H Goel, P Tanwar - Computer Methods and Programs …, 2022 - Elsevier
Background and objectives Remarkable infectivity of severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV2) is due to the rapid emergence of various strains which enable …

Molecular and computational analysis of spike protein of newly emerged omicron variant in comparison to the delta variant of SARS-CoV-2 in Iraq

PMA Rashid, GF Salih - Molecular biology reports, 2022 - Springer
Abstract Background The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)
has had a major impact on world health over the last 2 years. The emergence of SARS-CoV …

[HTML][HTML] Evaluation of immune evasion in SARS-CoV-2 Delta and Omicron variants

AM Chaudhari, M Joshi, D Kumar, A Patel… - Computational and …, 2022 - Elsevier
Emerging SARS-CoV-2 variants with higher transmissibility and immune escape remain a
persistent threat across the globe. This is evident from the recent outbreaks of the Delta (B …

[HTML][HTML] A comprehensive review on Covid-19 Omicron (B. 1.1. 529) variant

R Manjunath, SL Gaonkar, EAM Saleh… - Saudi journal of biological …, 2022 - Elsevier
The world has been combating different variants of SARS-COV-19 since its first outbreak in
Wuhan city. SARS-COV-19 is caused by the coronavirus. The corona virus mutates and …

Molecular determinants associated with temporal succession of SARS-CoV-2 variants in Uttar Pradesh, India

S Pal, P Mehta, A Pandey, A Ara, U Ghoshal… - Frontiers in …, 2023 - frontiersin.org
The emergence and rapid evolution of Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) caused a global crisis that required a detailed characterization of the …

Characteristic analysis of Omicron‐included SARS‐CoV‐2 variants of concern

H Yang, P Liu, Y Zhang, T Du, Y Zhou, S Lu… - MedComm, 2022 - Wiley Online Library
In view of the rapid development of the COVID‐19 pandemic and SARS‐CoV‐2 mutation,
we characterized the emerging SARS‐CoV‐2 variants of concern (VOCs) by both …