Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review

K Mohamed, N Yazdanpanah, A Saghazadeh… - Bioorganic …, 2021 - Elsevier
Background Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak,
there has been an increasing interest in finding a potential therapeutic agent for the disease …

[HTML][HTML] Computational methods directed towards drug repurposing for COVID-19: advantages and limitations

PP Sharma, M Bansal, A Sethi, L Pena, VK Goel… - RSC …, 2021 - pubs.rsc.org
Novel coronavirus disease 2019 (COVID-19) has significantly altered the socio-economic
status of countries. Although vaccines are now available against the severe acute …

[HTML][HTML] A comprehensive review of drug repurposing strategies against known drug targets of COVID-19

A Khataniar, U Pathak, S Rajkhowa, AN Jha - Covid, 2022 - mdpi.com
Drug repurposing is a more inexpensive and shorter approach than the traditional drug
discovery and development process. The concept of identifying a potent molecule from a …

[HTML][HTML] Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
In December 2019, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the causative agent of coronavirus disease 2019 (COVID-19) was first identified in the …

Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus

CA Omolo, N Soni, VO Fasiku, I Mackraj… - European Journal of …, 2020 - Elsevier
The global pandemic of coronavirus disease 2019 (COVID-19), caused by novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 7,273,958 …

[HTML][HTML] Boosting the arsenal against COVID-19 through computational drug repurposing

G Ciliberto, L Cardone - Drug discovery today, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) world health emergency is calling scientists for
unprecedented, huge investigation efforts to urgently answer key questions: what is the …

[HTML][HTML] Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies

GM Nitulescu, H Paunescu… - International …, 2020 - spandidos-publications.com
The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑
CoV‑2) focused many researchers attention to find treatments that can suppress …

[HTML][HTML] Therapeutics for COVID-19 and post COVID-19 complications: An update

D Basu, VP Chavda, AA Mehta - Current Research in Pharmacology and …, 2022 - Elsevier
Since its inception in late December 2020 in China, novel coronavirus has affected the
global socio-economic aspect. Currently, the world is seeking safe and effective treatment …

A comprehensive review on pharmacologic agents, immunotherapies and supportive therapeutics for COVID-19

K Sharun, R Tiwari, MI Yatoo, S Natesan, D Megawati… - Narra J, 2022 - narraj.org
The emergence of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …

COVID‐19 drug repurposing: a review of computational screening methods, clinical trials, and protein interaction assays

X Wang, Y Guan - Medicinal research reviews, 2021 - Wiley Online Library
The situation of coronavirus disease 2019 (COVID‐19) pandemic is rapidly evolving, and
medical researchers around the globe are dedicated to finding cures for the disease. Drug …