The differentiation and maturation of mesenchymal stem cells (MSCs) to mesodermal and
other lineages are known to be controlled by various extrinsic and intrinsic signals. The …

Alternative splicing (AS) is an essential mechanism in post-transcriptional regulation and
leads to protein diversity. It has been shown that AS is prevalent in metazoan genomes, and …

The alternative splicing of precursor mRNA is an essential mechanism for protein diversity. It
plays important biological roles, such as proliferation, differentiation and development of …

Complete information regarding transcriptional and posttranscriptional gene regulation in
stem cells is necessary to understand the regulation of self-renewal and differentiation …

Alternative splicing is an essential mechanism of gene regulation, giving rise to remarkable
protein diversity in higher eukaryotes. Epithelial-mesenchymal transition (EMT) is a …

Stem cells are characterized by their capability to self‐renew and terminally differentiate into
multiple cell types. Somatic or adult stem cells have a finite self‐renewal capacity and are …

Alternative splicing (AS) greatly expands the coding capacities of genomes by allowing the
generation of multiple mature mRNAs from a limited number of genes. Although the massive …

Development of highly anticipated stem cell-based therapies requires a
detailedunderstanding of mechanisms regulating biological properties of these cells …

A population of multipotent stromal cells exists within bone marrow and other adult tissues,
which is able to differentiate into different skeletal tissues such as bone, cartilage and fat …

Extensive studies have been performed to clarify the processes during which mesenchymal
stem cells (MSCs) differentiate into their lineage fates. In vitro differentiation of MSCs into …