Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: a double-blind randomized placebo-controlled …

YL Hurd, S Spriggs, J Alishayev… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Despite the staggering consequences of the opioid epidemic, limited nonopioid
medication options have been developed to treat this medical and public health crisis. This …

Cannabidiol and substance use disorder: Dream or reality

S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …

Cannabidiol as an intervention for addictive behaviors: a systematic review of the evidence

M Prud'homme, R Cata… - … abuse: research and …, 2015 - journals.sagepub.com
Drug addiction is a chronically relapsing disorder characterized by the compulsive desire to
use drugs and a loss of control over consumption. Cannabidiol (CBD), the second most …

Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms

C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …

Cannabidiol as a treatment for craving and relapse in individuals with cocaine use disorder: A randomized placebo‐controlled trial

V Mongeau‐Pérusse, S Brissette, J Bruneau… - …, 2021 - Wiley Online Library
ABSTRACT Background and Aims Cocaine use disorder (CUD) is a significant public health
concern for which no efficacious pharmacological interventions are available. Cannabidiol …

Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances

Y Ren, J Whittard, A Higuera-Matas… - Journal of …, 2009 - Soc Neuroscience
There remains debate regarding the impact of cannabis on neuropsychiatric disorders.
Here, we examined the effects of cannabidiol (CBD), a nonpsychoactive constituent of …

Cannabidiol in the context of substance use disorder treatment: A systematic review

V Paulus, J Billieux, A Benyamina, L Karila - Addictive behaviors, 2022 - Elsevier
Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …

Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems

J Moltke, C Hindocha - Journal of cannabis research, 2021 - Springer
Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

A cross-sectional study of cannabidiol users

J Corroon, JA Phillips - Cannabis and cannabinoid research, 2018 - liebertpub.com
Introduction: Preclinical and clinical studies suggest that cannabidiol (CBD) found in
Cannabis spp. has broad therapeutic value. CBD products can currently be purchased …

Safety and pharmacokinetics of oral cannabidiol when administered concomitantly with intravenous fentanyl in humans

AF Manini, G Yiannoulos… - Journal of addiction …, 2015 - journals.lww.com
Objectives: Cannabidiol (CBD) is hypothesized as a potential treatment for opioid addiction,
with safety studies an important first step for medication development. We determined CBD …