MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
Abstract RTS, S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium falciparum. In a phase 3 trial, RTS, S/AS01 showed vaccine efficacy against clinical malaria …
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …
KJ Wilby, TTY Lau, SE Gilchrist… - Annals of …, 2012 - journals.sagepub.com
Objective: To summarize and evaluate the literature for Mosquirix (RTS, S) and provide insight into the therapeutic and economic controversies of this novel malaria vaccine …
AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half of the world population is still exposed to the risk of contracting malaria. Developing an …
J Sacarlal, P Aide, JJ Aponte, M Renom… - Journal of Infectious …, 2009 - academic.oup.com
Background We previously reported that the RTS, S/AS02A vaccine had an acceptable safety profile, was immunogenic, and demonstrated efficacy against Plasmodium falciparum …
N Arora, LC Anbalagan, AK Pannu - Risk Management and …, 2021 - Taylor & Francis
Background Recent advances in mosquito eradication and antimalarial treatments have reduced the malaria burden only modestly. An effective malaria vaccine remains a high …
RTS, S is the most advanced candidate vaccine against human malaria. During its remarkable journey from conception and design in the early 1980s to the multicenter Phase …
Background Plasmodium falciparum malaria is a pressing global health problem. A previous study of the malaria vaccine RTS, S (which targets the circumsporozoite protein), given with …