[HTML][HTML] Full kinetic modeling analysis of [18F] fluorocholine Positron Emission Tomography (PET) at initial diagnosis of high-grade glioma

S Rubí, P Bibiloni, M Villar, M Brell, M Valiente… - NeuroImage: Clinical, 2024 - Elsevier
Purpose The main objective was to characterize the tracer uptake kinetics of [18 F]
fluoromethylcholine ([18 F] F-CHO) in high-grade gliomas (HGG) through a full PET kinetic …

Relationship of regional cerebral blood flow and kinetic behaviour of O-(2-18F-fluoroethyl)-L-tyrosine uptake in cerebral gliomas

K Zhang, KJ Langen, I Neuner, G Stoffels… - Nuclear medicine …, 2014 - journals.lww.com
Objectives O-(2-18 F-fluoroethyl)-L-tyrosine (18 F-FET) is an established tracer for brain
tumour imaging. 18 F-FET kinetics in gliomas appear to have potential for tumour grading …

The optimal timing for imaging brain tumours and other brain lesions with 18F-labelled fluoromethylcholine: a dynamic positron emission tomography study

K Mertens, J Bolcaen, H Ham, K Deblaere… - Nuclear medicine …, 2012 - journals.lww.com
Purpose To determine the optimal timing for imaging brain tumours and other brain lesions
with 18 F-labelled fluoromethylcholine (18 F-FCho) PET. Materials and methods Dynamic …

Promising role of [18F] fluorocholine PET/CT vs [18F] fluorodeoxyglucose PET/CT in primary brain tumors—Early experience

WWC Lam, DCE Ng, WY Wong, SC Ong… - Clinical neurology and …, 2011 - Elsevier
Primary brain tumors (PBT), in particular gliomas, are among the most difficult neoplasms to
treat, necessitating good quality imaging to guide clinicians at many junctures. Current …

Noninvasive quantification of 18F-FLT human brain PET for the assessment of tumour proliferation in patients with high-grade glioma

H Backes, R Ullrich, B Neumaier, L Kracht… - European journal of …, 2009 - Springer
Purpose Compartmental modelling of 3′-deoxy-3′-[18 F]-fluorothymidine (18 F-FLT) PET-
derived kinetics provides a method for noninvasive assessment of the proliferation rate of …

FDG, MET or CHO? The quest for the optimal PET tracer for glioma imaging continues

B Gulyás, I Nyáry, K Borbély - Nature Clinical Practice Neurology, 2008 - nature.com
Abstract This Practice Point commentary discusses a study by Kato et al. that assessed the
usefulness of three PET tracers—11C-methionine (MET), 18F-fluorodeoxyglucose, and 11C …

Quantification of O-(2-[18F]fluoroethyl)-L-tyrosine kinetics in glioma

T Koopman, N Verburg, RC Schuit, PJW Pouwels… - EJNMMI research, 2018 - Springer
Background This study identified the optimal tracer kinetic model for quantification of
dynamic O-(2-[18 F] fluoroethyl)-L-tyrosine ([18 F] FET) positron emission tomography (PET) …

Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L-tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat

N Spaeth, MT Wyss, J Pahnke, G Biollaz, A Lutz… - European journal of …, 2006 - Springer
Introduction The positron emission tomography (PET) tracers 18 F-fluoro-ethyl-L-tyrosine
(FET), 18 F-fluorocholine (N, N-dimethyl-N-[18 F] fluoromethyl-2-hydroxyethylammonium …

Simplified analysis of FET-kinetics in brain tumors by voxel-by-voxel linear regression

H Herzog, P Meyer, G Stoffels, F Floeth, H Coenen… - 2008 - Soc Nuclear Med
307 Objectives: PET-imaging with O-(2-[18 F] fluoroethyl)-L-tyrosine (FET) allows not only an
improved delineation of cerebral glioma, but also tumor grading based on FET kinetics. Low …

Effective Detection and Monitoring of Glioma Using [18F]FPIA PET Imaging

V Vassileva, M Braga, C Barnes, J Przystal, A Ashek… - Biomedicines, 2021 - mdpi.com
Background: Reprogrammed cellular metabolism is a cancer hallmark. In addition to
increased glycolysis, the oxidation of acetate in the citric acid cycle is another common …