[HTML][HTML] SARS-CoV-2 accessory proteins reveal distinct serological signatures in children

A Hachim, H Gu, O Kavian, M Mori, MYW Kwan… - Nature …, 2022 - nature.com
The antibody response magnitude and kinetics may impact clinical severity, serological
diagnosis and long-term protection of COVID-19, which may play a role in why children …

[HTML][HTML] SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19

S Ravichandran, J Tang, G Grubbs, Y Lee… - Nature …, 2021 - nature.com
There is limited understanding of the viral antibody fingerprint following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children. Herein, SARS-CoV …

[HTML][HTML] ORF8 and ORF3b antibodies are accurate serological markers of early and late SARS-CoV-2 infection

A Hachim, N Kavian, CA Cohen, AWH Chin… - Nature …, 2020 - nature.com
The SARS-CoV-2 virus emerged in December 2019 and has caused a worldwide pandemic
due to the lack of any pre-existing immunity. Accurate serology testing is urgently needed to …

[HTML][HTML] Cross-reactive antibody immunity against SARS-CoV-2 in children and adults

E Fraley, C LeMaster, D Banerjee, S Khanal… - Cellular & molecular …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel beta-coronavirus
that has emerged and caused a global pandemic of coronavirus disease 2019 (COVID-19) …

[PDF][PDF] Antibody landscape against SARS-CoV-2 reveals significant differences between non-structural/accessory and structural proteins

Y Li, Z Xu, Q Lei, D Lai, H Hou, H Jiang, Y Zheng… - Cell Reports, 2021 - cell.com
The immunogenicity of the SARS-CoV-2 proteome is largely unknown, especially for non-
structural proteins and accessory proteins. In this study, we collect 2,360 COVID-19 sera and …

[HTML][HTML] The landscape of antibody binding in SARS-CoV-2 infection

AS Heffron, SJ McIlwain, MF Amjadi, DA Baker… - PLoS …, 2021 - journals.plos.org
The search for potential antibody-based diagnostics, vaccines, and therapeutics for
pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has focused …

[HTML][HTML] Comparison of antibody responses to SARS-CoV-2 variants in Australian children

ZQ Toh, N Mazarakis, J Nguyen, RA Higgins… - Nature …, 2022 - nature.com
There is limited understanding of antibody responses in children across different SARS-CoV-
2 variants. As part of an ongoing household cohort study, we assessed the antibody …

[PDF][PDF] Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs

CI Stoddard, J Galloway, HY Chu, MM Shipley, K Sung… - Cell Reports, 2021 - cell.com
A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope …

Beyond the Spike: identification of viral targets of the antibody responses to SARS-CoV-2 in COVID-19 patients

A Hachim, N Kavian, CA Cohen, AWH Chin, DKW Chu… - MedRxiv, 2020 - medrxiv.org
Abstract Background The SARS-CoV-2 virus emerged in December 2019 and caused a
pandemic associated with a spectrum of COVID-19 disease ranging from asymptomatic to …

[HTML][HTML] SARS-CoV-2 accessory protein ORF8 decreases antibody-dependent cellular cytotoxicity

G Beaudoin-Bussières, A Arduini, C Bourassa… - Viruses, 2022 - mdpi.com
Viruses use many different strategies to evade host immune responses. In the case of SARS-
CoV-2, its Spike mutates rapidly to escape from neutralizing antibodies. In addition to this …