Effects of chronic oral probiotic treatment in paclitaxel-induced neuropathic pain

M Cuozzo, V Castelli, C Avagliano, A Cimini… - Biomedicines, 2021 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) represents one of the most prevalent
and potentially disabling side effects due to the use of anticancer drugs, one of the primary …

[HTML][HTML] Probiotic DSF counteracts chemotherapy induced neuropathic pain

V Castelli, P Palumbo, M d'Angelo, NK Moorthy… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Problem statement: Chemotherapy-induced peripheral neuropathy (CIPN) is a widespread
and potentially disabling side effect of various anticancer drugs. In spite of the intensive …

Fecal microbiota transplantation alleviated paclitaxel-induced peripheral neuropathy by interfering with astrocytes and TLR4/p38MAPK pathway in rats

H Shi, M Chen, C Zheng, B Yinglin… - Journal of Pain …, 2023 - Taylor & Francis
Purpose Paclitaxel-induced peripheral neuropathy (PIPN) constitutes a refractory and
progressive adverse consequence of paclitaxel treatment, causing pain and sensory …

Dominant role of the gut microbiota in chemotherapy induced neuropathic pain

C Ramakrishna, J Corleto, PM Ruegger, GD Logan… - Scientific reports, 2019 - nature.com
Chemotherapy induced peripheral neuropathy (CIPN), a toxic side effect of some cancer
treatments, negatively impacts patient outcomes and drastically reduces survivor's quality of …

Gut microbiota modulation and its implications on neuropathic pain: a comprehensive literature review

A Corriero, M Giglio, F Inchingolo, A Moschetta… - Pain and Therapy, 2024 - Springer
Neuropathic pain (NP) is a chronic pain disorder arising from somatosensory nervous
system impairment. Extensive evidence supports the notion that the gut microbiota (GM) is …

The influence of dietary supplementations on neuropathic pain

F D'Egidio, G Lombardozzi… - Life, 2022 - mdpi.com
Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory
nervous system and affects 7–10% of the worldwide population. Neuropathic pain can be …

Gut microbiota depletion by antibiotics ameliorates somatic neuropathic pain induced by nerve injury, chemotherapy, and diabetes in mice

P Ma, R Mo, H Liao, C Qiu, G Wu, C Yang… - Journal of …, 2022 - Springer
Background Gut microbiota has been found involved in neuronal functions and neurological
disorders. Whether and how gut microbiota impacts chronic somatic pain disorders remain …

Microbiota and pain: save your gut feeling

C Morreale, I Bresesti, A Bosi, A Baj, C Giaroni… - Cells, 2022 - mdpi.com
Recently, a growing body of evidence has emerged regarding the interplay between
microbiota and the nervous system. This relationship has been associated with several …

Role of complement in a rat model of paclitaxel-induced peripheral neuropathy

J Xu, L Zhang, M Xie, Y Li, P Huang… - The Journal of …, 2018 - journals.aai.org
Chemotherapy-induced peripheral neuropathy (CIPN) is a painful and debilitating side effect
of cancer chemotherapy with an unclear pathogenesis. Consequently, the available …

Gut microbiota is critical for the induction of chemotherapy-induced pain

S Shen, G Lim, Z You, W Ding, P Huang, C Ran… - Nature …, 2017 - nature.com
Chemotherapy-induced pain is a dose-limiting condition that affects 30% of patients
undergoing chemotherapy. We found that gut microbiota promotes the development of …