Human umbilical cord endothelial cells (HUVECs) obtained from women affected by
gestational diabetes (GD‐HUVECs) display durable pro‐atherogenic modifications and …

Advanced glycation end products (AGEs), produced by the non-enzymatic glycation of
proteins and lipids under hyperglycemia or oxidative stress conditions, has been implicated …

Purpose: Features of cellular senescence have been described in diabetic retinal
vasculature. The aim of this study was to investigate how the high glucose microenvironment …

Diabetic vasculopathy is central to the development of diverse cardiovascular, renal, retinal,
and neurological complications of diabetes. We previously demonstrated that growth of …

Vascular aging is based on the development of endothelial dysfunction, which is thought to
be promoted by senescent cells accumulating in aged tissues and is possibly affected by …

Endothelial progenitor cells (EPCs) exhibit impaired function in the context of diabetes, and
advanced glycation end products (AGEs), which accumulate in diabetes, may contribute to …

We have previously found that nonenzymatically glycated collagen I (GC), mimicking
diabetic microenvironment, can induce senescent phenotype in early passage human …

Diabetes and ageing induce reduction and dysfunction of vascular progenitor cells.
Advanced glycation endproducts (AGEs) accumulate in diabetes and ageing. We …

Impaired glucose tolerance characterized by postprandial hyperglycemia, which occurs
frequently in elderly persons and represents an important preliminary step in diabetes …

In diabetes, some of the cellular changes are similar to aging. We hypothesized that
hyperglycemia accelerates aging-like changes in the endothelial cells (ECs) and tissues …