RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery

Y Ding, B Lv, J Zheng, C Lu, J Liu, Y Lei, M Yang… - Journal of Controlled …, 2022 - Elsevier
Hyper-inflammation associated with cytokine storm syndrome causes high mortality in
patients with COVID-19. Glucocorticoids, such as methylprednisolone sodium succinate …

[HTML][HTML] Dry powder comprised of isoniazid-loaded nanoparticles of hyaluronic acid in conjugation with mannose-anchored chitosan for macrophage-targeted …

M Mukhtar, N Csaba, S Robla, R Varela-Calviño… - Pharmaceutics, 2022 - mdpi.com
Marketed dosage forms fail to deliver anti-tubercular drugs directly to the lungs in pulmonary
Tuberculosis (TB). Therefore, nanomediated isoniazid (INH)-loaded dry powder for …

Microencapsulated chitosan nanoparticles for lung protein delivery

A Grenha, B Seijo, C Remuñán-López - European journal of …, 2005 - Elsevier
It has already been demonstrated that spray drying is a very valuable technique for
producing dry powders adequate for pulmonary delivery of drugs. We have developed …

Red blood cell-hitchhiking mediated pulmonary delivery of ivermectin: Effects of nanoparticle properties

J Zheng, C Lu, Y Ding, J Zhang, F Tan, J Liu… - International journal of …, 2022 - Elsevier
Recent studies have demonstrated that ivermectin (IVM) exhibits antiviral activity against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of …

Supramolecular erythrocytes-hitchhiking drug delivery system for specific therapy of acute pneumonia

J Li, Y Ding, Q Cheng, C Gao, J Wei, Z Wang… - Journal of Controlled …, 2022 - Elsevier
Acute pneumonia is an inflammatory syndrome often associated with severe multi-organ
dysfunction and high mortality. The therapeutic efficacy of current anti-inflammatory …

[HTML][HTML] Targeted delivery of antibiotics to the infected pulmonary tissues using ROS-responsive nanoparticles

Y Wang, Q Yuan, W Feng, W Pu, J Ding… - Journal of …, 2019 - Springer
Background Immunocompromised individuals and those with lung dysfunction readily
acquire pulmonary bacterial infections, which may cause serious diseases and carry a …

[HTML][HTML] Macrophage biomimetic nanocarriers for anti-inflammation and targeted antiviral treatment in COVID-19

Q Tan, L He, X Meng, W Wang, H Pan, W Yin… - Journal of …, 2021 - Springer
Background The worldwide pandemic of COVID-19 remains a serious public health menace
as the lack of efficacious treatments. Cytokine storm syndrome (CSS) characterized with …

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

A García-Fernández, M Sancho, V Bisbal… - Journal of Controlled …, 2021 - Elsevier
Acute lung injury (ALI) is a critical inflammatory syndrome, characterized by increased
diffuse inflammation and severe lung damage, which represents a clinical concern due to …

Neutrophil membranes coated, antibiotic agent loaded nanoparticles targeting to the lung inflammation

K Wang, Y Lei, D Xia, P Xu, T Zhu, Z Jiang… - Colloids and Surfaces B …, 2020 - Elsevier
Natural cellular membranes, with the outstanding qualities of biocompatibility and specificity,
have gained growing attentions in the system of drug delivery. Nanoparticles coated with …

Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles

IM El-Sherbiny, HDC Smyth - Molecular pharmaceutics, 2012 - ACS Publications
This study involves a promising approach to achieve sustained pulmonary drug delivery. Dry
powder particulate carriers were engineered to allow simultaneous aerosol lung delivery …