The influence of apical periodontitis on circulatory inflammatory mediators in peripheral blood: A prospective case–control study

AC Georgiou, JWR Twisk, W Crielaard… - International …, 2023 - Wiley Online Library
Aim To explore the influence of apical periodontitis (AP) on inflammatory markers in blood of
otherwise healthy individuals and to depict the inflammatory profile of the healing after …

Apical periodontitis is associated with elevated concentrations of inflammatory mediators in peripheral blood: a systematic review and meta-analysis

AC Georgiou, W Crielaard, I Armenis, R de Vries… - Journal of …, 2019 - Elsevier
Introduction Apical periodontitis (AP), except for the local known consequences, may also be
a systemic burden. Circulating inflammatory mediators that are released to sustain the AP …

Can apical periodontitis affect serum levels of CRP, IL-2, and IL-6 as well as induce pathological changes in remote organs?

J Zhang, X Huang, B Lu, C Zhang, Z Cai - Clinical Oral Investigations, 2016 - Springer
Objectives The aim of this study was to investigate whether apical periodontitis (AP) could
cause systemic cytokine elevation and pathological changes in remote organs in an …

Can apical periodontitis modify systemic levels of inflammatory markers? A systematic review and meta-analysis

MS Gomes, TC Blattner, M Sant'Ana Filho… - Journal of …, 2013 - Elsevier
Introduction This systematic review and meta-analysis investigated evidence to support
whether apical periodontitis (AP) can modify the systemic levels of inflammatory markers …

Endodontic infections increase leukocyte and lymphocyte levels in the blood

RO Samuel, JE Gomes-Filho, MM Azuma… - Clinical Oral …, 2018 - Springer
Objectives The aim of this study was to determine whether the presence of single or multiple
apical periodontitis (AP) alters blood cell counts and cytokine production. Material and …

The impact of apical periodontitis, non‐surgical root canal retreatment and periapical surgery on serum inflammatory biomarkers

A Bakhsh, D Moyes, G Proctor… - International …, 2022 - Wiley Online Library
Aim The aim of the study was to measure serum levels of molecular markers of inflammation
in patients undergoing non‐surgical root canal retreatment (Re‐RCT) and periapical surgery …

[HTML][HTML] The influence of apical periodontitis on the concentration of inflammatory mediators in peripheral blood plasma and the metagenomic profiling of endodontic …

AC Georgiou, W Crielaard, P Ouwerling… - Contemporary Clinical …, 2021 - Elsevier
Increased systemic inflammation has been identified in presence of oral disease, specifically
endodontic disease. It is important to investigate whether treatment of the oral disease …

Multiple apical periodontitis influences serum levels of cytokines and nitric oxide

LTA Cintra, RO Samuel, MM Azuma… - Journal of …, 2016 - Elsevier
Introduction This study evaluated whether apical periodontitis (AP) in a single tooth or in
multiple teeth affected serum levels of inflammatory mediators and influenced blood …

How does the periapical inflammatory process compromise general health?

IJ Márton - Endodontic Topics, 2004 - Wiley Online Library
Several lines of evidence support the causative role of oral inflammatory lesions and certain
systemic diseases, such as atherosclerosis and cardiovascular diseases, adverse …

Aging as a risk factor on the immunoexpression of pro-inflammatory IL-1β, IL-6 and TNF-α cytokines in chronic apical periodontitis lesions

QE Teixeira, DC Ferreira, AMP da Silva, LS Gonçalves… - Biology, 2021 - mdpi.com
Simple Summary Apical periodontitis often manifests as a chronic and asymptomatic
disease. The formation of chronic apical periodontitis lesion (CAPL) occurs due an …