[HTML][HTML] MiR-155 is involved in renal ischemia-reperfusion injury via direct targeting of FoxO3a and regulating renal tubular cell pyroptosis

H Wu, T Huang, L Ying, C Han, D Li, Y Xu… - Cellular physiology and …, 2016 - karger.com
Background/Aims: Ischemia/reperfusion injury (IRI) plays a crucial role in renal
transplantation and can cause renal failure associated with pyroptosis, a pro-inflammatory …

Identification of MicroRNA-92a-3p as an essential regulator of tubular epithelial cell pyroptosis by targeting Nrf1 via HO-1

R Wang, H Zhao, Y Zhang, H Zhu, Q Su, H Qi… - Frontiers in …, 2021 - frontiersin.org
Renal ischemia–reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) and has
no effective treatment. Exploring the molecular mechanisms of renal IRI is critical for the …

miR-98 protects endothelial cells against hypoxia/reoxygenation induced-apoptosis by targeting caspase-3

H Li, Y Meng, Q Xie, W Yi, X Lai, Q Bian, J Wang… - Biochemical and …, 2015 - Elsevier
Endothelial dysfunction is one of the main pathophysiological processes involved in renal
ischemia reperfusion injury. Our previous microarray study demonstrated that miR-98 was …

MiR‐21‐3p plays a crucial role in metabolism alteration of renal tubular epithelial cells during sepsis associated acute kidney injury via AKT/CDK2‐FOXO1 pathway

Z Lin, Z Liu, X Wang, C Qiu… - BioMed research …, 2019 - Wiley Online Library
Objective. Sepsis and associated acute kidney injury (SAKI) are determined to be closely
related to poor prognosis. Because the metabolic alterations of tubular epithelial cells …

Exosome‐mediated pyroptosis of miR‐93‐TXNIP‐NLRP3 leads to functional difference between M1 and M2 macrophages in sepsis‐induced acute kidney injury

CX Juan, Y Mao, Q Cao, Y Chen… - Journal of cellular …, 2021 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome caused by infection, resulting in
organ dysfunction. Sepsis‐induced acute kidney injury (AKI) is one of the most common …

miR-30c-5p Alleviated Pyroptosis During Sepsis-Induced Acute Kidney Injury via Targeting TXNIP

X Li, L Yao, X Zeng, B Hu, X Zhang, J Wang, R Zhu… - Inflammation, 2021 - Springer
Sepsis-induced acute kidney injury (SAKI) is a common complication of hospitalized
patients, often leading to unacceptable mortality. Limited effective treatment or diagnosis …

[PDF][PDF] MiR-942-5p alleviates septic acute kidney injury by targeting FOXO3.

N Luo, HM Gao, YQ Wang, HJ Li… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: Sepsis refers to the systemic inflammatory response caused by infection. Acute
kidney injury (AKI) in sepsis is very common, and there are many complicated mechanisms …

Inhibition of miR-155 ameliorates acute kidney injury by apoptosis involving the regulation on TCF4/Wnt/β-catenin pathway

XB Zhang, X Chen, DJ Li, GN Qi, YQ Dai, J Gu… - Nephron, 2019 - karger.com
Background: Acute kidney injury (AKI) is a complex clinical disorder with sudden decay in
renal function. Ischemia-reperfusion injury (IRI) has been regarded as the main etiology for …

miR-182-5p and miR-378a-3p regulate ferroptosis in I/R-induced renal injury

C Ding, X Ding, J Zheng, B Wang, Y Li, H Xiang… - Cell death & …, 2020 - nature.com
Renal tubular cell death is the key factor of the pathogenesis of ischemia/reperfusion (I/R)
kidney injury. Ferroptosis is a type of regulated cell death (RCD) found in various diseases …

MiR-132-3p activation aggravates renal ischemia-reperfusion injury by targeting Sirt1/PGC1alpha axis

C Li, S Han, J Zhu, F Cheng - Cellular Signalling, 2023 - Elsevier
The pathogenesis of renal ischemic diseases remains unclear. In this study, we demonstrate
the induction of microRNA-132-3p (miR-132-3p) in ischemic acute kidney injury (AKI) and …