Aging is accompanied by a progressive decline in immune function, known as
immunosenescence, which renders elderly individuals more susceptible to infections …

One of the most appreciated consequences of immunosenescence is an impaired response
to vaccines with advanced age. While most studies report impaired antibody responses in …

The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …

Older adults are more susceptible to viral and bacterial infection, and experience higher
incidence and severity of infectious diseases. Although vaccination is the most logical …

Immunosenescence is characterized by a progressive deterioration of the immune system
associated with aging. Multiple components of both innate and adaptive immune systems …

The aging immune system demonstrates a reduced capacity to mount a robust immune
response (immunosenescence), thereby increasing the susceptibility to various infectious …

Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …

People with advanced age have a higher susceptibility to infections and exhibit increased
mortality and morbidity as the ability of the immune system to combat infections decreases …

Immunosenescence increases the risk and severity of diseases in elderly individuals and
leads to impaired vaccine-induced immunity. With aging of the global population and the …

It is widely accepted that ageing is accompanied by remodelling of the immune system,
including reduced numbers of naïve T cells, increased senescent or exhausted T cells …