A major obstacle for treatment of HCC is the inadequate efficacy and limitation of the
available therapeutic options. Despite the recent advances in developing novel treatment …

Hepatocellular carcinoma (HCC) is currently the fifth most common malignancy and the third
leading cause of cancer-related mortalities worldwide. In the last few years, treatments for …

Hepatocellular carcinoma (HCC) is currently the third leading cause of malignancy-related
mortalities worldwide. Natural killer (NK) cells are involved in the critical role of first line …

Background Natural killer (NK) cells play major roles in eliminating tumor cells. Preliminary
studies have shown that NK cells and their receptors/ligands have prognostic value in …

Hepatocellular carcinoma (HCC) remains an important complication of chronic liver disease,
especially when cirrhosis occurs. Existing treatment strategies include surgery, loco-regional …

Natural killer (NK) cells account for 25–50% of the total number of hepatic lymphocytes,
which implicates that NK cells play an important role in liver immunity. The frequencies of …

Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1) are specific innate lymphoid
cell subsets that are key for the detection and elimination of pathogens and cancer cells. In …

Nature killer (NK) cells play a critical role in host innate and adaptive immune defense
against viral infections and tumors. NK cells are enriched in liver hematopoietic cells with …

Natural killer (NK) cells are involved in the pathogenesis of hepatitis C viral (HCV) infection
and hepatocellular carcinoma (HCC). Recent immunological progresses have revealed the …

Hepatocellular carcinoma (HCC) is a global health burden with increasing incidence, poor
prognosis and limited therapeutic options. Natural killer (NK) cells exhibit potent anti-tumoral …