Big GABA: Edited MR spectroscopy at 24 research sites
M Mikkelsen, PB Barker, PK Bhattacharyya, MK Brix… - Neuroimage, 2017 - Elsevier
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …
Gannet: A batch‐processing tool for the quantitative analysis of gamma‐aminobutyric acid–edited MR spectroscopy spectra
Purpose The purpose of this study is to describe the Gannet toolkit for the quantitative batch
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …
Impact of frequency drift on gamma‐aminobutyric acid‐edited MR spectroscopy
Purpose To investigate the quantitative impact of frequency drift on Gamma‐Aminobutyric
acid (GABA+)‐edited MRS of the human brain at 3 Tesla (T). Methods Three sequential …
acid (GABA+)‐edited MRS of the human brain at 3 Tesla (T). Methods Three sequential …
Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites
Accurate and reliable quantification of brain metabolites measured in vivo using 1 H
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …
Multi-vendor standardized sequence for edited magnetic resonance spectroscopy
Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …
Subtraction artifacts and frequency (Mis‐)alignment in J‐difference GABA editing
Purpose To compare the repeatability of γ‐aminobutyric acid (GABA) measurements using J‐
difference editing, before and after spectral realignment—a technique which has previously …
difference editing, before and after spectral realignment—a technique which has previously …
Tissue correction for GABA‐edited MRS: Considerations of voxel composition, tissue segmentation, and tissue relaxations
Purpose To develop a tissue correction for GABA‐edited magnetic resonance spectroscopy
(MRS) that appropriately addresses differences in voxel gray matter (GM), white matter …
(MRS) that appropriately addresses differences in voxel gray matter (GM), white matter …
Spectral‐editing measurements of GABA in the human brain with and without macromolecule suppression
Purpose The conventional spectral‐editing experiment used to measure GABA in the human
brain also contains a contribution from macromolecules (MM), and the combined GABA plus …
brain also contains a contribution from macromolecules (MM), and the combined GABA plus …
A practical guide to robust detection of GABA in human brain by J-difference spectroscopy at 3 T using a standard volume coil
γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in human brain and has
been implicated in several neuropsychiatric disorders. In vivo human brain GABA …
been implicated in several neuropsychiatric disorders. In vivo human brain GABA …
3D GABA imaging with real-time motion correction, shim update and reacquisition of adiabatic spiral MRSI
Gamma-aminobutyric acid (GABA) and glutamate (Glu) are the major neurotransmitters in
the brain. They are crucial for the functioning of healthy brain and their alteration is a major …
the brain. They are crucial for the functioning of healthy brain and their alteration is a major …