A new hope for a devastating disease: hydrogen sulfide in Parkinson's disease

X Cao, L Cao, L Ding, J Bian - Molecular Neurobiology, 2018 - Springer
Hydrogen sulfide (H 2 S) has been regarded as the third gaseous transmitter alongside nitric
oxide (NO) and carbon monoxide (CO). In mammalian brain, H 2 S is produced redundantly …

Hydrogen sulfide: neurophysiology and neuropathology

LF Hu, M Lu, PT Hon Wong, JS Bian - Antioxidants & redox signaling, 2011 - liebertpub.com
Hydrogen sulfide (H2S) was known to be a toxic gas and an environmental hazard for many
decades. However, it is now recognized that H2S may serve as a gaseous mediator that is …

Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models

LF Hu, M Lu, CX Tiong, GS Dawe, G Hu, JS Bian - Aging cell, 2010 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder characterized by a progressive
loss of dopaminergic neurons in the substantia nigra (SN). The present study was designed …

Hydrogen sulfide functions as a neuromodulator to regulate striatal neurotransmission in a mouse model of P arkinson's disease

M Wang, J Zhu, Y Pan, J Dong, L Zhang… - Journal of …, 2015 - Wiley Online Library
Hydrogen sulfide (H2S), a novel endogenous gasotransmitter, has been considered a
neuromodulator to enhance hippocampal long‐term potentiation and exerts neuroprotective …

Hydrogen sulfide: a novel signaling molecule in the central nervous system

BH Tan, PTH Wong, JS Bian - Neurochemistry international, 2010 - Elsevier
Hydrogen sulfide is an endogenously produced gas in the central nervous system and has
been touted as the body's third gaseous signaling molecule after nitric oxide and carbon …

Neuroprotective effects of hydrogen sulfide in Parkinson's disease animal models: methods and protocols

X Xue, JS Bian - Methods in enzymology, 2015 - Elsevier
Hydrogen sulfide (H 2 S) was first proposed to be a neuromodulator in 1996. After that,
multiple biological functions of H 2 S have been revealed. In brain, it regulates intracellular …

Hydrogen sulfide in physiological and pathological mechanisms in brain

M Kumar, R Sandhir - … (Formerly Current Drug Targets-CNS & …, 2018 - ingentaconnect.com
Background & Objective: Hydrogen sulfide [H2S] has been widely known as a toxic gas for
more than 300 years in the scientific community. However, the understanding about this …

Evaluation of the antiparkinsonism and neuroprotective effects of hydrogen sulfide in acute 6-hydroxydopamine-induced animal model of Parkinson's disease …

M Sarukhani, H Haghdoost-Yazdi… - Neurological …, 2018 - Taylor & Francis
Introduction: Studies have shown that hydrogen sulfide (H2S), a gaseous neurotransmitter,
has neuroprotective effect. Here, we evaluated the neuroprotective activity of H2S in acute 6 …

Brain, Learning, and Memory: Role of H2S in Neurodegenerative Diseases

BV Nagpure, JS Bian - Chemistry, biochemistry and pharmacology of …, 2015 - Springer
For more than 300 years, the toxicity of hydrogen sulfide (H 2 S) has been known to
mankind. However, this point of view is changing as an increased interest was observed in …

[HTML][HTML] Hydrogen sulfide, nitric oxide, and neurodegenerative disorders

S Panthi, S Manandhar, K Gautam - Translational Neurodegeneration, 2018 - Springer
Abstract Hydrogen Sulfide (H 2 S) and Nitric Oxide (NO) have become recognized as
important gaseous signaling molecules with enormous pharmacological effects, therapeutic …