Current understanding of how extracorporeal membrane oxygenators activate haemostasis and other blood components

AJ Doyle, BJ Hunt - Frontiers in medicine, 2018 - frontiersin.org
Extracorporeal membrane oxygenators are used in critical care for the management of
severe respiratory and cardiac failure. Activation of the coagulation system is initiated by the …

Anticoagulation strategies during extracorporeal membrane oxygenation: a narrative review

S Rajsic, R Breitkopf, D Jadzic… - Journal of Clinical …, 2022 - mdpi.com
The development of extracorporeal life support technology has added a new dimension to
the care of critically ill patients who fail conventional treatment options. Extracorporeal …

Hemostatic changes during extracorporeal membrane oxygenation: a prospective randomized clinical trial comparing three different extracorporeal membrane …

MV Malfertheiner, A Philipp, M Lubnow… - Critical care …, 2016 - journals.lww.com
Objective: Extracorporeal membrane oxygenation is a rescue therapy for patients with
severe lung failure. Major complications caused by extracorporeal membrane oxygenation …

Novel surfaces in extracorporeal membrane oxygenation circuits

A Ontaneda, GM Annich - Frontiers in medicine, 2018 - frontiersin.org
The balance between systemic anticoagulation and clotting is challenging. In normal
hemostasis, the endothelium regulates the balance between anticoagulant and …

Multi-modal characterization of the coagulopathy associated with extracorporeal membrane oxygenation

T Granja, K Hohenstein, P Schüssel… - Critical Care …, 2020 - journals.lww.com
Objectives: Extracorporeal membrane oxygenation is used to stabilize severe
cardiocirculatory and/or respiratory failure. However, extracorporeal membrane oxygenation …

Coagulation and anticoagulation in extracorporeal membrane oxygenation

W Muntean - Artificial organs, 1999 - Wiley Online Library
The hemostatic system poses a major problem in extracorporeal membrane oxygenation
(ECMO). The foreign surface in the extracorporeal circuit activates platelets and the clotting …

Low flow rate alters haemostatic parameters in an ex-vivo extracorporeal membrane oxygenation circuit

KK Ki, MR Passmore, CHH Chan… - Intensive care medicine …, 2019 - Springer
Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality used
to manage cardiopulmonary failure refractory to conventional medical and surgical …

[HTML][HTML] Hematologic concerns in extracorporeal membrane oxygenation

J Sniderman, P Monagle, GM Annich… - Research and Practice in …, 2020 - Elsevier
This ISTH “State of the Art” review aims to critically evaluate the hematologic considerations
and complications in extracorporeal membrane oxygenation (ECMO). ECMO is …

Flow-induced platelet activation in components of the extracorporeal membrane oxygenation circuit

G Fuchs, N Berg, LM Broman, L Prahl Wittberg - Scientific reports, 2018 - nature.com
Extracorporeal membrane oxygenation (ECMO) is used for rescue in severe respiratory
and/or circulatory failure. The patient's blood is pumped over artificial surfaces in the ECMO …

Hemolysis and plasma free hemoglobin during extracorporeal membrane oxygenation support: from clinical implications to laboratory details

N Dufour, A Radjou, M Thuong - ASAIO Journal, 2020 - journals.lww.com
Venovenous and venoarterial extracorporeal membrane oxygenation (ECMO) are lifesaving
supports that are more and more frequently used in critically ill patients. Despite of major …