Background A growing number of epidemiological studies indicate that metabolic syndrome
(MetS) and its associated features play a key role in the development of certain …

Berberine, the main bioactive component of Coptis chinensis Franch., is widely used in the
treatment of diabetes. Previous studies have reported that berberine supplementation may …

Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Context• Having been used for thousands of years to treat gastrointestinal diseases, the
natural isoquinoline alkaloid, berberine, has exhibited a wide spectrum of biochemical and …

Berberine (a protoberberine isoquinoline alkaloid) has shown promising pharmacological
activities, including analgesic, anti-inflammatory, anticancer, antidiabetic, anti …

Purpose Several meta-analyses reported berberine (BBR) supplementation improves
glycemic parameters and inflammatory marker, but findings remain inconsistent. Therefore …

Diabetes is a group of metabolic disorders with an increased risk of developing cognitive
impairment and dementia. The hippocampus in the forebrain contains an abundance of …

This study is aimed to investigate the protective effect against type 2 diabetes mellitus
(T2DM) and Alzheimer's disease (AD) of Berberine (BBR), and the underlying mechanism of …

Objective. Rhizoma Coptidis is an herb that has been frequently used in many traditional
formulas for the treatment of diabetic mellitus (DM) over thousands of years. Berberine, the …

Background: Memory-impairment was one of the common characteristics in patients with
diabetes mellitus. The release of chronic inflammation mediators and insulin resistance in …