During recent decades, a great variety of viral and host targets have been exploited for the
discovery of antiviral agents against human infectious diseases. 1 Although significant …

The prevalence of chronic viral infectious diseases, such as human immunodeficiency virus
(HIV), hepatitis C virus (HCV), and influenza virus; the emergence and re-emergence of new …

Three decades of antiviral drugs | Nature Reviews Drug Discovery Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

A decade ago, just five drugs were licensed for the treatment of viral infections. Since then,
greater understanding of viral life cycles, prompted in particular by the need to combat …

Early vaccine development for coronavirus disease 2019 (COVID-19) was possible thanks
to the prior knowledge that the main immunogenic protein of coronaviruses is the spike …

Covering: up to April 2014 The development of drugs with broad-spectrum antiviral activities
is a long pursued goal in drug discovery. It has been shown that blocking co-opted host …

The ten stories told here deal with (i) ribavirin as an inhibitor of IMP dehydrogenase and (ii)
ribavirin, in combination with pegylated interferon, as the present “standard of care” for …

Viruses are obligatory intracellular parasites, whose replication depends on pathways and
functions of the host cell. Consequently, it is difficult to define virus-specific functions as …

Abstract The 30th International Conference on Antiviral Research (ICAR) was held in
Atlanta, GA, USA from May 18 to 21, 2017. This report provides an account of award …

This review article presents the fifth part (part E) in the series of stories on antiviral drug
discovery. The ten stories belonging to this fifth part are dealing with (i) aurintricarboxylic …