Mitochondria are essential organelles for cellular energy production, metabolic
homeostasis, calcium homeostasis, cell proliferation, and apoptosis. About 99% of …

Mitochondria are essential organelles which perform complex and varied functions within
eukaryotic cells. Maintenance of mitochondrial health and functionality is thus a key cellular …

Mitochondria play a critical role in providing energy, maintaining cellular metabolism, and
regulating cell survival and death. To carry out these crucial functions, mitochondria employ …

Mitochondria are essential for the viability of eukaryotic cells as they perform crucial
functions in bioenergetics, metabolism and signalling and have been associated with …

The majority of proteins localised to mitochondria are encoded by the nuclear genome, with
approximately 1500 proteins imported into mammalian mitochondria. Dysfunction in this …

Mitochondria fulfill central functions in bioenergetics, metabolism, and apoptosis. They
import more than 1,000 different proteins from the cytosol. It had been assumed that the …

By generating the majority of a cell's ATP, mitochondria permit a vast range of reactions
necessary for life. Mitochondria also perform other vital functions including biogenesis and …

Mitochondria are pivotal organelles for cellular signaling and metabolism, and their
dysfunction leads to severe cellular stress. About 60-70% of the mitochondrial proteome …

The human mitochondrial outer membrane is biophysically unique as it is the only
membrane possessing transmembrane β-barrel proteins (mitochondrial outer membrane …

Mitochondria hold diverse and pivotal roles in fundamental processes that govern cell
survival, differentiation, and death, in addition to organismal growth, maintenance, and …