[HTML][HTML] Microglia polarization from M1 to M2 in neurodegenerative diseases

S Guo, H Wang, Y Yin - Frontiers in aging neuroscience, 2022 - frontiersin.org
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Microglial polarization: novel therapeutic mechanism against Alzheimer's disease

K Yao, H Zu - Inflammopharmacology, 2020 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease that results in
progressive dementia, and exhibits high disability and fatality rates. Recent evidence has …

Microglia polarization in Alzheimer's disease: mechanisms and a potential therapeutic target

Q Wang, H Yao, W Liu, B Ya, H Cheng… - Frontiers in aging …, 2021 - frontiersin.org
Neuroinflammation regulated by microglia is one of the important factors involved in the
pathogenesis of Alzheimer's disease (AD). Activated microglia exhibited phenotypes termed …

[HTML][HTML] Pharmacological modulation of functional phenotypes of microglia in neurodegenerative diseases

GJ Song, K Suk - Frontiers in aging neuroscience, 2017 - frontiersin.org
Microglia are the resident innate immune cells of the central nervous system that mediate
brain homeostasis maintenance. Microglia-mediated neuroinflammation is a hallmark …

Role of microglia in neurological disorders and their potentials as a therapeutic target

L Du, Y Zhang, Y Chen, J Zhu, Y Yang… - Molecular neurobiology, 2017 - Springer
Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …

Role of microglial m1/m2 polarization in relapse and remission of psychiatric disorders and diseases

Y Nakagawa, K Chiba - Pharmaceuticals, 2014 - mdpi.com
Psychiatric disorders such as schizophrenia and major depressive disorder were thought to
be caused by neurotransmitter abnormalities. Patients with these disorders often experience …

Natural products as a potential modulator of microglial polarization in neurodegenerative diseases

X Jin, MY Liu, DF Zhang, X Zhong, K Du, P Qian… - Pharmacological …, 2019 - Elsevier
abstract Neurodegenerative diseases (NDs) are characterized by the progressive loss of
structure and function of neurons most common in elderly population, mainly including …

Differential roles of M1 and M2 microglia in neurodegenerative diseases

Y Tang, W Le - Molecular neurobiology, 2016 - Springer
One of the most striking hallmarks shared by various neurodegenerative diseases, including
Parkinson's disease, Alzheimer's disease (AD), and amyotrophic lateral sclerosis, is …

The role of microglia in the development of neurodegeneration

AR Saitgareeva, KV Bulygin, IF Gareev, OA Beylerli… - Neurological …, 2020 - Springer
Microglia-mediated central nervous system (CNS) inflammation is one of the key features of
various neurodegenerative diseases, including Parkinson's and Alzheimer's diseases. In the …

[HTML][HTML] Microglia in neuroinflammation and neurodegeneration: from understanding to therapy

L Muzio, A Viotti, G Martino - Frontiers in Neuroscience, 2021 - frontiersin.org
Microglia are the resident macrophages of the central nervous system (CNS) acting as the
first line of defense in the brain by phagocytosing harmful pathogens and cellular debris …