[HTML][HTML] Should we apply a treatable traits approach to asthma care?

J Melhorn, I Howell, ID Pavord - Annals of Allergy, Asthma & Immunology, 2022 - Elsevier
Objective To explore the evidence for adopting a “treatable traits” approach to asthma
management. Data Sources PubMed, Medline, and Google Scholar. Study Selections The …

Targeting treatable traits in severe asthma: a randomised controlled trial

VM McDonald, VL Clark… - European …, 2020 - Eur Respiratory Soc
Rationale Treatable traits have been proposed as a new paradigm for airway disease
management. Objectives To characterise treatable traits in a severe asthma population and …

[HTML][HTML] Bringing the treatable traits approach to primary care asthma management

PE Pfeffer, H Rupani, A De Simoni - Frontiers in Allergy, 2023 - frontiersin.org
Asthma continues to be a major cause of illness with a significant mortality, despite its
increasing range of treatments. Adoption of a treatable traits approach in specialist centres …

Impact of treatable traits on asthma control and quality of life

SMJ Janssen, HAC van Helvoort, TA Tjalma… - The Journal of Allergy …, 2023 - Elsevier
Background Many adult patients with asthma have uncontrolled disease and impaired
quality of life, despite current asthma-specific drug therapies. Objective This study aimed to …

Management of severe asthma: from stepwise approach to therapy to treatable traits?

G Wang, VM McDonald… - Precision Clinical Medicine, 2021 - academic.oup.com
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation.
The disease affects more than 300 million individuals worldwide, and poses a significant …

Treatable Traits in Asthma: The importance of extra-pulmonary traits-GERD, CRSwNP, Atopic Dermatitis, and Depression/Anxiety

VM McDonald, Y Hamada, A Agusti… - The Journal of Allergy and …, 2024 - Elsevier
Treatable traits is a personalised medicine approach to the management of airway disease.
Assessing traits within the three domains of pulmonary, extra pulmonary and …

[HTML][HTML] Treatable traits in the European U‐BIOPRED adult asthma cohorts

AJ Simpson, PP Hekking, DE Shaw, LJ Fleming… - Allergy, 2019 - ncbi.nlm.nih.gov
3| DISCUSSION The identification of treatable traits facilitates a precision medicine strategy
for the management of airways disease, that is free from the traditional diagnostic labels and …

An update on asthma diagnosis

C Armeftis, C Gratziou, N Siafakas… - Journal of …, 2023 - Taylor & Francis
Objective Asthma imposes a significant health and socioeconomic burden with an average
prevalence impacting 5-10% of the global population. The aim of this narrative review is to …

Treatable traits that predict health status and treatment response in airway disease

SA Hiles, PG Gibson, A Agusti, VM McDonald - The Journal of Allergy and …, 2021 - Elsevier
Background A strategy based on the assessment and management of treatable traits (TTs)
has been proposed as a new paradigm in airway disease. There is a potentially long list of …

Treatable traits can be identified in a severe asthma registry and predict future exacerbations

VM McDonald, SA Hiles, K Godbout, ES Harvey… - …, 2019 - Wiley Online Library
Background and objective A new taxonomic and management approach, termed treatable
traits, has been proposed for airway diseases including severe asthma. This study examined …