We present the largest whole-genome sequencing (WGS) study of non-small cell lung
cancer (NSCLC) to date among 6,004 individuals of Chinese ancestry, coupled with 23,049 …

Background Germline genetic variation contributes to lung cancer (LC) susceptibility.
Previous genome-wide association studies (GWAS) have implicated susceptibility loci …

Recent studies suggest that rare variants exhibit stronger effect sizes and might play a
crucial role in the etiology of lung cancers (LC). Whole exome plus targeted sequencing of …

Abstract Knowledge of the lung cancer genome has experienced rapid growth over the past
decade. Genome-wide association studies and sequencing studies have identified dozens …

Background Genome-wide association studies are widely used to map genomic regions
contributing to lung cancer (LC) susceptibility, but they typically do not identify the precise …

To identify genetic variation associated with lung cancer risk, we performed a genome-wide
association analysis of 685 lung cancer cases that had a family history of two or more first or …

Background There are two main types of lung cancer: small cell lung cancer (SCLC) and
non-small cell lung cancer (NSCLC). NSCLC has many subtypes, but the two most common …

Adenocarcinoma (AC) and squamous cell carcinoma (SqCC) are two major histological
subtypes of lung cancer. Genome-wide association studies (GWAS) have made …

Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …

Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not …