Increased serum levels of IL-17A and IL-23 are associated with decreased vitamin D3 and increased pain in osteoarthritis

A Askari, MM Naghizadeh, R Homayounfar, A Shahi… - PLoS one, 2016 - journals.plos.org
Introduction Osteoarthritis (OA) is the most common type of arthritis and proinflammatory
cytokines have been considered as the main etiologic factor in the pathogenesis of the …

Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotype

SJB Snelling, S Bas, GJ Puskas, SG Dakin, D Suva… - PloS one, 2017 - journals.plos.org
Purpose Osteoarthritis (OA) is a common and heterogeneous arthritic disorder. Patients
suffer pain and their joints are characterized by articular cartilage loss and osteophyte …

Interleukin (IL)-17A, F and AF in inflammation: a study in collagen-induced arthritis and rheumatoid arthritis

S Sarkar, S Justa, M Brucks, J Endres… - Clinical & …, 2014 - academic.oup.com
Summary Interleukin (IL)-17 plays a critical role in inflammation. Most studies to date have
elucidated the inflammatory role of IL-17A, often referred to as IL-17. IL-17F is a member of …

Elevated circulating IL-17 level is associated with inflammatory arthritis and disease activity: a meta-analysis

X Zhang, Y Yuan, Z Pan, Y Ma, M Wu, J Yang, R Han… - Clinica Chimica …, 2019 - Elsevier
Objectives Previous studies found that the interleukin (IL)-17 level was elevated in
inflammatory arthritis, but results were inconsistent. This meta-analysis aimed to investigate …

Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis …

LGM van Baarsen, MC Lebre, D van der Coelen… - Arthritis research & …, 2014 - Springer
Introduction Accumulating evidence suggests an important role for interleukin 17 (IL-17) in
the pathogenesis of several inflammatory diseases, including rheumatoid arthritis (RA) and …

Association between IL-17 gene polymorphisms and circulating IL-17 levels in osteoarthritis: a meta-analysis.

YH Lee, GG Song - Zeitschrift für Rheumatologie, 2020 - search.ebscohost.com
Osteoarthritis (OA) is the most common joint disease; it primarily affects the knees, hips,
hands, and spine [1]. OA is characterized by the progressive degeneration of articular …

Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis

L Melis, B Vandooren, E Kruithof, P Jacques… - Annals of the …, 2010 - ard.bmj.com
Objectives Th17 cells are an effector T-cell population that plays a role in chronic
inflammatory conditions and is dependent on IL-23 for their survival and expansion. More …

Role of interleukin-23 as a biomarker in rheumatoid arthritis patients and its correlation with disease activity

DSE Zaky, EMA El-Nahrery - International immunopharmacology, 2016 - Elsevier
Background IL-23 is a pro-inflammatory cytokine belonging to the IL-12 cytokine family. IL-
23 is essential for the differentiation of Th17 lymphocytes, a subtype of T lymphocyte …

IL-17 in osteoarthritis: A narrative review

J Xiao, P Zhang, FL Cai, CG Luo, T Pu, XL Pan… - Open life …, 2023 - degruyter.com
Osteoarthritis (OA) is a painful joint disease that is common among the middle-aged and
elderly populations, with an increasing prevalence. Therapeutic options for OA are limited …

IL-17 levels in synovium of patients with rheumatoid arthritis, psoriatic arthritis and osteoarthritis: Target validation in various forms of arthritis

LGM Van Baarsen, MC Lebre… - Annals of the …, 2011 - ard.bmj.com
Background Accumulating evidence suggests an important role for interleukin 17 (IL-17) in
the pathogenesis of several inflammatory diseases, including rheumatoid arthritis (RA). IL …