Treatment choices for the “severe acute respiratory syndrome‐related coronavirus‐2 (SARS‐
CoV‐2)” are inadequate, having no clarity on efficacy and safety profiles. Currently, no …

Background At present, no single efficacious therapeutic exists for acute COVID-19
management and a multimodal approach may be necessary. 2-deoxy-d-glucose (2-DG) is a …

Virus infections can cause tissue damage in many ways. Severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), a cause of the current COVID-19 pandemic, has been …

Viral infection almost invariably causes metabolic changes in the infected cell and several
types of host cells that respond to the infection. Among metabolic changes, the most …

Glucose, the primary substrate for ATP synthesis, is catabolized during glycolysis to
generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic …

COVID-19 is an infectious disease caused by Coronavirus 2 (SARS-CoV-2) that may lead to
a severe acute respiratory syndrome. Such syndrome is thought to be related, at least in …

Aims Virus-infected host cells switch their metabolism to a more glycolytic phenotype,
required for new virion synthesis and packaging. Therefore, we investigated the effect and …

The severity and mortality of COVID-19 are associated with pre-existing medical
comorbidities such as diabetes mellitus. However, the underlying causes for increased …

The COVID-19 pandemic as the largest global public health crisis is now considered as an
emergency at the World Health Organization (WHO). As there is no specific therapy for …

COVID-19 is caused by the SARS-CoV-2 virus, which has afflicted more than 245.37 million
individuals worldwide and resulted in more than 4.9 million deaths as of today, with a …