Microglia-mediated neuroinflammation in neurodegenerative diseases

CS Subhramanyam, C Wang, Q Hu… - Seminars in cell & …, 2019 - Elsevier
Microglia, being the resident immune cells of the central nervous system, play an important
role in maintaining tissue homeostasis and contributes towards brain development under …

Microglia in neurological diseases: a road map to brain-disease dependent-inflammatory response

S Bachiller, I Jiménez-Ferrer, A Paulus… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia represent a specialized population of macrophages-like cells in the central
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

JA Smith, A Das, SK Ray, NL Banik - Brain research bulletin, 2012 - Elsevier
Microglia are activated in response to a number of different pathological states within the
CNS including injury, ischemia, and infection. Microglial activation results in their production …

The role of microglia in the development of neurodegeneration

AR Saitgareeva, KV Bulygin, IF Gareev, OA Beylerli… - Neurological …, 2020 - Springer
Microglia-mediated central nervous system (CNS) inflammation is one of the key features of
various neurodegenerative diseases, including Parkinson's and Alzheimer's diseases. In the …

Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …

Microglia and neurodegeneration: the role of systemic inflammation

C Cunningham - Glia, 2013 - Wiley Online Library
It is well accepted that CNS inflammation has a role in the progression of chronic
neurodegenerative disease, although the mechanisms through which this occurs are still …

Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer's disease

D Singh - Journal of neuroinflammation, 2022 - Springer
Neuroinflammation is instigated by the misfiring of immune cells in the central nervous
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

H González, D Elgueta, A Montoya… - Journal of …, 2014 - Elsevier
Neuroinflammation constitutes a fundamental process involved in the progression of several
neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease …

Role of microglia in neurological disorders and their potentials as a therapeutic target

L Du, Y Zhang, Y Chen, J Zhu, Y Yang… - Molecular neurobiology, 2017 - Springer
Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …

Microglia dynamics in aging-related neurobehavioral and neuroinflammatory diseases

N Javanmehr, K Saleki, P Alijanizadeh… - Journal of …, 2022 - Springer
Microglia represent the first line of immune feedback in the brain. Beyond immune
surveillance, they are essential for maintaining brain homeostasis. Recent research has …