Role of the TRPC1 channel in hippocampal long-term depression and in spatial memory extinction

X Yerna, O Schakman, I Ratbi, A Kreis… - International journal of …, 2020 - mdpi.com
Group I metabotropic glutamate receptors (mGluR) are involved in various forms of synaptic
plasticity that are believed to underlie declarative memory. We previously showed that …

Activation of TRPC1 channel by metabotropic glutamate receptor mGluR5 modulates synaptic plasticity and spatial working memory

S Lepannetier, R Gualdani, S Tempesta… - Frontiers in cellular …, 2018 - frontiersin.org
Group I metabotropic glutamate receptors, in particular mGluR5, have been implicated in
various forms of synaptic plasticity that are believed to underlie declarative memory. We …

mGluR1/TRPC3-mediated synaptic transmission and calcium signaling in mammalian central neurons

J Hartmann, HA Henning… - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Metabotropic glutamate receptors type 1 (mGluR1s) are required for a normal function of the
mammalian brain. They are particularly important for synaptic signaling and plasticity in the …

Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca2+ wave‐dependent activation of SK and TRPC channels

L El‐Hassar, AM Hagenston… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary The hippocampus is a neural structure that is critical for some forms
of memory function. It performs this function through the ability of its neurons to fire patterns …

Role of transient receptor potential channel 1 (TRPC1) in glutamate-induced cell death in the hippocampal cell line HT22

KL Narayanan, S Subramaniam, CP Bengston… - Journal of molecular …, 2014 - Springer
Transient receptor potential channel 1 (TRPC1; a cation channel activated by store
depletion and/or through an intracellular messenger) is expressed in a variety of tissues …

Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long‐term potentiation and spatial reference memory in the dentate gyrus of freely …

K Naie, D Manahan‐Vaughan - European Journal of …, 2005 - Wiley Online Library
Group I metabotropic glutamate receptors (mGluRs) are critically required for multiple forms
of hippocampal synaptic plasticity in vivo. The role of the receptor subtype mGluR1 in long …

Mechanisms of metabotropic glutamate receptor‐mediated synaptic signalling in cerebellar Purkinje cells

J Hartmann, A Konnerth - Acta physiologica, 2009 - Wiley Online Library
The metabotropic glutamate receptors type 1 (mGluR1s) are required for a normal function
of the mammalian cerebellum. These G‐protein‐coupled receptors are abundantly …

TRPC1 regulates the activity of a voltage-dependent nonselective cation current in hippocampal CA1 neurons

F Kepura, E Braun, A Dietrich, TD Plant - Cells, 2020 - mdpi.com
The cation channel subunit TRPC1 is strongly expressed in central neurons including
neurons in the CA1 region of the hippocampus where it forms complexes with TRPC4 and …

Slow synaptic transmission mediated by TRPV1 channels in CA3 interneurons of the hippocampus

N Eguchi, A Hishimoto, I Sora, M Mori - Neuroscience Letters, 2016 - Elsevier
Metabotropic glutamate receptors (mGluRs) modulate various neuronal functions in the
central nervous system. Many studies reported that mGluRs have linkages to neuronal …

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

YM Lu, Z Jia, C Janus, JT Henderson… - Journal of …, 1997 - Soc Neuroscience
Class I metabotropic glutamate receptors (mGluRs) have been postulated to play a role in
synaptic plasticity. To test the involvement of one member of this class, we have recently …