El cáncer ovárico epitelial (COE) posee la tasa de mortalidad más alta entre los cánceres
ginecológicos en el mundo, siendo en Chile la segunda causa de muerte por neoplasias …

El cáncer ovárico epitelial (COE) es una neoplasia ginecológica y presenta una alta
mortalidad a nivel mundial. Uno de sus mecanismos, es la interacción del factor de …

Metformin known as the first-line orally prescribed drug for lowering blood glucose in type II
diabetes (T2DM) has recently found various therapeutic applications including in cancer …

AIMS: To investigate the effect of metformin on the expression profiles of microRNAs in
human pancreatic cancer cells. METHODS: MicroRNAs real-time PCR Array was applied to …

Background: Metformin has been reported to inhibit the growth of various types of cancers,
including breast cancer. Yet the mechanisms underlying the anticancer effects of metformin …

An unexplored molecular scenario that might explain the inhibitory impact of the anti-
diabetic drug metformin on the genesis of breast cancer relates to metformin's ability to …

Accumulating evidence suggests that metformin, a biguanide class of anti-diabetic drugs,
possesses anti-cancer properties and may reduce cancer risk and improve prognosis …

ABSTRACT Preclinical Research MicroRNAs (miRNAs) are a family of short, noncoding, 19–
23 base pair RNA molecules. Due to their unique role in gene regulation in various tissues …

Introducción: El cáncer ovárico epitelial (COE) es una de las neoplasias ginecológicas más
letales. Este se caracteriza por la aparición tardía e inespecífica de síntomas y por una …

Metformin, a drug approved for diabetes type II treatment, has been associated with a
reduction in the incidence of breast cancer and metastasis and increased survival in diabetic …