Pancreatic amyloid is found in more than 95% of type II diabetes patients. Pancreatic
amyloid is formed by the aggregation of islet amyloid polypeptide (hIAPP or amylin), which is …

Amyloid aggregates have been recognized to be a pathological hallmark of several fatal
diseases, including Alzheimer's disease, the prion-related diseases, and type II diabetes …

Human islet amyloid polypeptide (hIAPP) accumulates as pancreatic amyloid in type 2
diabetes and readily forms fibrils in vitro. Investigations into the mechanism of hIAPP fibril …

The islet amyloid polypeptide (hIAPP) is a 37 amino acid residue polypeptide that was found
to accumulate as amyloid fibrils in the pancreas of individuals with type II diabetes. Previous …

The human islet amyloid polypeptide (hIAPP) or amylin, a neuroendocrine peptide hormone,
is known to misfold and form amyloidogenic aggregates that have been observed in the …

Human islet amyloid polypeptide (IAPP) is the major component of amyloid deposits found
in the pancreas of over 90% of all cases of type-2 diabetes. We have generated a series of …

The development of type II diabetes was shown to be associated with the formation of
amyloid fibrils consisted of the islet amyloid polypeptide (IAPP or amylin). Recently, a short …

Islet amyloid is found in many patients suffering from type 2 diabetes. Amyloid fibrils found
deposited in the pancreatic islets are composed of a 37-residue peptide, known as islet …

Insoluble amyloid formation by islet amyloid polypeptide (IAPP) in the islets of Langerhans
of the pancreas is a major pathophysiological feature of noninsulin dependent diabetes …

Amylin, also known as islet amyloid polypeptide (IAPP), is the major protein component of
the fibril deposits found in the pancreas of individuals with type II diabetes. The central …