Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …

[HTML][HTML] Neutralizing monoclonal antibodies for COVID-19 treatment and prevention

JP Jaworski - biomedical journal, 2021 - Elsevier
The SARS-CoV-2 pandemic has caused unprecedented global health and economic crises.
Several vaccine approaches and repurposed drugs are currently under evaluation for safety …

Emerging antibody-based therapeutics against SARS-CoV-2 during the global pandemic

Y Sun, M Ho - Antibody therapeutics, 2020 - academic.oup.com
SARS-CoV-2 antibody therapeutics are being evaluated in clinical and preclinical stages. As
of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike …

[HTML][HTML] Targeting SARS-CoV2 spike protein receptor binding domain by therapeutic antibodies

A Hussain, A Hasan, MMN Babadaei, SH Bloukh… - Biomedicine & …, 2020 - Elsevier
As the number of people infected with the newly identified 2019 novel coronavirus (SARS-
CoV2) is continuously increasing every day, development of potential therapeutic platforms …

[HTML][HTML] Monoclonal antibody as a potential anti-COVID-19

L Jahanshahlu, N Rezaei - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one
of top priorities for scientists to develop novel treatment strategies. Researchers are racing to …

[HTML][HTML] Development and application of therapeutic antibodies against COVID-19

L Ning, HB Abagna, Q Jiang, S Liu… - International journal of …, 2021 - ncbi.nlm.nih.gov
The pandemic of Coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2) continues to be a global health crisis …

Development of a SARS-CoV-2 total antibody assay and the dynamics of antibody response over time in hospitalized and nonhospitalized patients with COVID-19

EH Vogelzang, FC Loeff, NIL Derksen… - The Journal of …, 2020 - journals.aai.org
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infections often cause only
mild disease that may evoke relatively low Ab titers compared with patients admitted to …

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

SJ Zost, P Gilchuk, RE Chen, JB Case, JX Reidy… - Nature medicine, 2020 - nature.com
Antibodies are a principal determinant of immunity for most RNA viruses and have promise
to reduce infection or disease during major epidemics. The novel coronavirus SARS-CoV-2 …

[HTML][HTML] Identification of human single-domain antibodies against SARS-CoV-2

Y Wu, C Li, S Xia, X Tian, Y Kong, Z Wang, C Gu… - Cell host & …, 2020 - cell.com
The worldwide spread of COVID-19 highlights the need for an efficient approach to rapidly
develop therapeutics and prophylactics against SARS-CoV-2. The SARS-CoV-2 spike …

[HTML][HTML] Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2

G Zhou, Q Zhao - International Journal of Biological Sciences, 2020 - ncbi.nlm.nih.gov
A newly identified novel coronavirus (SARS-CoV-2) is causing pneumonia-associated
respiratory syndrome across the world. Epidemiology, genomics, and pathogenesis of the …