Crosstalk between RNA m6A modification and non-coding RNA contributes to cancer growth and progression

F Dai, Y Wu, Y Lu, C An, X Zheng, L Dai, Y Guo… - … Therapy-Nucleic Acids, 2020 - cell.com
N6-methyladenosine (m 6 A) is the most common RNA modification and has an important
role in normal development and tumorigenesis. The abnormal expression of m 6 A …

Non-coding RNA m6A modification in cancer: mechanisms and therapeutic targets

DH Chen, JG Zhang, CX Wu, Q Li - Frontiers in cell and …, 2021 - frontiersin.org
Recently, N6-methyl-adenosine (m6A) ribonucleic acid (RNA) modification, a critical and
common internal RNA modification in higher eukaryotes, has generated considerable …

Interaction between N6-methyladenosine (m6A) modification and noncoding RNAs in cancer

Y Chen, Y Lin, Y Shu, J He, W Gao - Molecular cancer, 2020 - Springer
As a critical internal RNA modification in higher eukaryotes, N 6-methyladenosine (m 6 A)
has become the hotspot of epigenetics research in recent years. Extensive studies on …

N6‑methyladenine RNA modification and cancer

J Yang, J Chen, X Fei, X Wang… - Oncology …, 2020 - spandidos-publications.com
Abstract N6‑methyladenosine (m6A) in messenger RNA (mRNA) is regulated by m6A
methyltransferases and demethylases. Modifications of m6A are dynamic and reversible …

The interplay between m6A RNA methylation and noncoding RNA in cancer

S Ma, C Chen, X Ji, J Liu, Q Zhou, G Wang… - Journal of hematology & …, 2019 - Springer
Abstract N6-methyladenosine (m6A) methylation, one of the most common RNA
modifications, has been reported to execute important functions that affect normal life …

m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer

H Huang, H Weng, J Chen - Cancer cell, 2020 - cell.com
N 6-Methyladenosine (m 6 A) RNA modification has emerged in recent years as a new layer
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …

The role of N6-methyladenosine-modified non-coding RNAs in the pathological process of human cancer

L Luo, Y Zhen, D Peng, C Wei, X Zhang, X Liu… - Cell death …, 2022 - nature.com
Non-coding RNAs (ncRNAs) account for the majority of the widespread transcripts of
mammalian genomes. They rarely encode proteins and peptides, but their regulatory role is …

RNA m6A modification in cancers: molecular mechanisms and potential clinical applications

C Gu, X Shi, C Dai, F Shen, G Rocco, J Chen, Z Huang… - The innovation, 2020 - cell.com
N 6-Methyladenosine (m 6 A) RNA modification brings a new dawn for RNA modification
researches in recent years. This posttranscriptional RNA modification is dynamic and …

The role of M6A modification in the regulation of tumor-related lncRNAs

Y Lan, B Liu, H Guo - Molecular Therapy-Nucleic Acids, 2021 - cell.com
N 6-methyladenosine (m 6 A) is the most abundant modification in eukaryotic cells, and it
regulates RNA transcription, processing, splicing, degradation, and translation. Long non …

The roles and implications of RNA m6A modification in cancer

X Deng, Y Qing, D Horne, H Huang… - Nature Reviews Clinical …, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …