Early-life adversity affects long-term health outcomes but there is considerable
interindividual variability in susceptibility to environmental influences. We proposed that …

Psychobiological models of allostatic load have delineated the effects of multiple processes
that contribute to risk for psychopathology. This approach has been fruitful, but the …

Rationale Past research has established an association between childhood and adolescent
stressors and elevated inflammatory and metabolic biomarkers in adulthood, but questions …

Childhood poverty is linked to a host of physical and psychological disorders during
childhood and later in life. In the study reported here, we showed that the proportion of …

While emotionality is often thought of as a risk factor, differential susceptibility theory argues
that emotionality reflects susceptibility to both positive and negative environmental …

Allostatic load (AL) is a measure of overall physiological wear-and-tear over the life course,
which could partially be the consequence of early life exposures. AL could allow a better …

Objectives: This study examines how the effects of childhood socioeconomic status (SES)
may carry on into late adulthood. Methods: We examine how childhood SES affects both …

Objective This study aimed to examine relationships between adverse childhood
experiences (ACEs) and related life events and allostatic load (AL)—“wear and tear” from …

The present study examined the concurrent and prospective, longitudinal effects of
childhood negative emotionality and self-regulation on allostatic load (AL), a physiological …

Abstract Adverse Childhood Experiences (ACEs) are stressful and/or traumatic experiences
associated with an increased lifetime risk of negative health outcomes. The Allostatic Load …