[HTML][HTML] Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome

S Chotikavanich, CS de Paiva, JJ Chen… - … & visual science, 2009 - arvojournals.org
purpose. To evaluate production and activity of metalloproteinase (MMP)-9 on the ocular
surface of patients with dysfunctional tear syndrome (DTS) and determine any correlation …

Matrix metalloproteinase 9 testing in dry eye disease using a commercially available point-of-care immunoassay

EM Messmer, V von Lindenfels, A Garbe, A Kampik - Ophthalmology, 2016 - Elsevier
Purpose To measure matrix metalloproteinase 9 (MMP-9) in the tear film of patients with dry
eye disease (DED) compared with controls and to correlate clinical findings. Design In a …

Tear cytokine profiles in dysfunctional tear syndrome

H Lam, L Bleiden, CS De Paiva, W Farley… - American journal of …, 2009 - Elsevier
PURPOSE: To compare tear cytokine and chemokine concentrations in asymptomatic
control and Dysfunctional Tear syndrome (DTS) patients and determine the correlations …

Matrix metalloproteinase 9 and transglutaminase 2 expression at the ocular surface in patients with different forms of dry eye disease

P Aragona, MH Aguennouz, L Rania, E Postorino… - Ophthalmology, 2015 - Elsevier
Objective To evaluate the expression of matrix metalloproteinase 9 (MMP9) and
transglutaminase 2 (TG2) in different forms of dry eye. Design Case control study …

Sensitivity and specificity of a point-of-care matrix metalloproteinase 9 immunoassay for diagnosing inflammation related to dry eye

R Sambursky, WF Davitt, R Latkany… - JAMA …, 2013 - jamanetwork.com
Objectives To determine the clinical sensitivity, specificity, negative predictive value, and
positive predictive value of a rapid point-of-care diagnostic test to detect elevated matrix …

[HTML][HTML] Correlation of tear inflammatory cytokines and matrix metalloproteinases with four dry eye diagnostic tests

KR VanDerMeid, SP Su, KW Ward… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: Tear cytokines and matrix metalloproteinases (MMPs) can be extracted from the
Schirmer strip. This study examined the extracted levels of tear cytokines and MMPs from …

Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye

SC Pflugfelder, W Farley, L Luo, LZ Chen… - The American journal of …, 2005 - Elsevier
Altered corneal epithelial barrier function is the cause for ocular irritation and visual
morbidity in dry eye disease. Increased matrix metalloproteinase (MMP)-9 activity has been …

Correlation of tear film osmolarity and 2 different MMP-9 tests with common dry eye tests in a cohort of non–dry eye patients

M Schargus, S Ivanova, V Kakkassery, HB Dick… - Cornea, 2015 - journals.lww.com
Purpose: Given that early-stage dry eye is difficult to diagnose, the purpose of this study was
to evaluate the performance of matrix metalloproteinase 9 (MMP-9) and tear film osmolarity …

Inflammatory markers in the tears of patients with ocular surface disease

A Acera, G Rocha, E Vecino, I Lema, JA Durán - Ophthalmic research, 2008 - karger.com
Purpose: To determine the concentration of interleukins (IL-1β and-6) and matrix
metalloproteinase 9 (pro-MMP-9) in the tears of patients with different ocular surface …

[HTML][HTML] Tear levels and activity of matrix metalloproteinase (MMP)-1 and MMP-9 in vernal keratoconjunctivitis

A Leonardi, P Brun, G Abatangelo… - … & visual science, 2003 - arvojournals.org
purpose. To study levels and activity of matrix metalloproteinase (MMP)-1 and-9 and their
tissue inhibitor (TIMP-1) in tears of patients with vernal keratoconjunctivitis (VKC), with and …