[HTML][HTML] High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection

EM Jacobsen, D Fabricius, M Class, F Topfstedt… - Nature …, 2022 - nature.com
The COVID-19 course and immunity differ in children and adults. We analyzed immune
response dynamics in 28 families up to 12 months after mild or asymptomatic infection …

[PDF][PDF] Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults

D Joshi, LE Nyhoff, VI Zarnitsyna, A Moreno… - Iscience, 2023 - cell.com
As SARS-CoV-2 becomes endemic, it is critical to understand immunity following early-life
infection. We evaluated humoral responses to SARS-CoV-2 in 23 infants/young children …

[HTML][HTML] SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies

K Lima, JC Fontoura, PO de Souza, T Fazolo… - Frontiers in …, 2022 - frontiersin.org
This is the third year of the SARS-CoV-2 pandemic, and yet most children remain
unvaccinated. COVID-19 in children manifests as mostly mild or asymptomatic, however …

[HTML][HTML] Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection

AC Dowell, MS Butler, E Jinks, G Tut, T Lancaster… - Nature …, 2022 - nature.com
SARS-CoV-2 infection is generally mild or asymptomatic in children but a biological basis for
this outcome is unclear. Here we compare antibody and cellular immunity in children (aged …

[HTML][HTML] Long-lived immunity in SARS-CoV-2-Recovered children and its neutralizing capacity against omicron

J Sieber, M Mayer, K Schmidthaler, S Kopanja… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection is effectively controlled by humoral and cellular immune responses.
However, the durability of immunity in children as well as the ability to neutralize variants of …

Children develop strong and sustained cross-reactive immune responses against spike protein following SARS-CoV-2 infection

AC Dowell, MS Butler, E Jinks, G Tut, T Lancaster… - 2021 - pesquisa.bvsalud.org
ABSTRACT SARS-CoV-2 infection is generally mild or asymptomatic in children but the
biological basis for this is unclear. We studied the profile of antibody and cellular immunity in …

Naturally-acquired immunity dynamics against SARS-CoV-2 in children and adolescents

T Patalon, Y Saciuk, H Ohayon Hadad, G Perez… - medRxiv, 2022 - medrxiv.org
Objectives There are paucity of studies examining naturally acquired immunity against
SARS-CoV-2 in children and adolescents, though they are generally the last group to be …

[HTML][HTML] Assessment of SARS-CoV-2 immunity in convalescent children and adolescents

HW Tsang, GT Chua, KKW To, JSC Wong… - Frontiers in …, 2021 - frontiersin.org
Persistence of protective immunity for SARS-CoV-2 is important against reinfection.
Knowledge on SARS-CoV-2 immunity in pediatric patients is currently lacking. We opted to …

[HTML][HTML] Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination

N Nziza, Y Deng, L Wood, N Dhanoa… - Nature …, 2024 - nature.com
Although young children generally experience mild symptoms following infection with SARS-
CoV-2, severe acute and long-term complications can occur. SARS-CoV-2 mRNA vaccines …

Considering mandatory vaccination of children for COVID-19

SA Plotkin, O Levy - Pediatrics, 2021 - publications.aap.org
Herculean efforts are ongoing to develop vaccines against the severe acute respiratory
syndrome 2 new coronavirus that causes the disease known as coronavirus disease 2019 …