EXOGENOUS Sex Hormones and Sex Hormone Receptor Modulators in COVID‐19: Rationale and Clinical Pharmacology Considerations

P Zou, A Heath, C Sewell, Y Lu… - Clinical Pharmacology …, 2022 - Wiley Online Library
Male patients with coronavirus disease 2019 (COVID‐19) fare much worse than female
patients in COVID‐19 severity and mortality according to data from several studies. Because …

Sex Hormones in COVID-19 Severity: The Quest for Evidence and Influence Mechanisms

H Xiao, L Yuan, J Li, C Zhang, G Liu, X Liu - 2023 - preprints.org
Studies report variable effects of sex hormones on serious diseases. Severe disease and
mortality rates in COVID-19 show marked gender differences that may be related to sex …

[HTML][HTML] Global sex disparity of COVID-19: a descriptive review of sex hormones and consideration for the potential therapeutic use of hormone replacement therapy in …

SC Okpechi, JT Fong, SS Gill, JC Harman… - Aging and …, 2021 - ncbi.nlm.nih.gov
Abstract The 2019-2020 SARS-related coronavirus-2 (SARS-CoV-2) pandemic has brought
unprecedented challenges to healthcare sectors around the world. As of November 2020 …

An overview of sex hormones in relation to SARS-CoV-2 infection

MSG Naz, M Banaei, S Dashti, FR Tehrani - Future Virology, 2021 - Taylor & Francis
Aim: Sex differences in COVID-19 outcomes might be explained from a sex hormones
(SexHs) perspective. Materials & methods: PubMed, Scopus, Web of Science, EMBASE and …

[HTML][HTML] Sex-tailored pharmacology and COVID-19: Next steps towards appropriateness and health equity

A Spini, V Giudice, V Brancaleone, MG Morgese… - Pharmacological …, 2021 - Elsevier
Making gender bias visible allows to fill the gaps in knowledge and understand health
records and risks of women and men. The coronavirus disease 2019 (COVID-19) pandemic …

[HTML][HTML] Immuno-endocrinology of COVID-19: the key role of sex hormones

F Tramontana, S Battisti, N Napoli… - Frontiers in …, 2021 - frontiersin.org
Epidemiological evidence shows clear gender disparities in the Coronavirus 2019 Disease
(COVID-19) severity and fatality. This may reflect the contribution of gender-related factors …

Sex disparities in COVID-19 severity and outcome: are men weaker or women stronger?

R Pivonello, RS Auriemma, C Pivonello, AM Isidori… - …, 2021 - karger.com
Abstract The coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health issue which has …

[HTML][HTML] Selective estrogen receptor modulators in COVID-19: a possible therapeutic option?

A Calderone, F Menichetti, F Santini… - Frontiers in …, 2020 - frontiersin.org
Male and female genders exhibit significant differences in the outcome of infective diseases
caused by several viral pathogens. Along with behavioral or social factors which can affect …

[HTML][HTML] Gender disparity in COVID-19: Role of sex steroid hormones

A Lipsa, JS Prabhu - Asian Pacific journal of tropical medicine, 2021 - journals.lww.com
The emerging pandemic of COVID-19 caused by the novel pathogenic human coronavirus
SARS-CoV-2 has caused significant morbidity and mortality across the globe, prompting the …

[HTML][HTML] Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?

ML Brandi - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Emerging evidence suggests that the novel Coronavirus disease-2019 (COVID-19) is
deadlier for men than women both in China and in Europe. Male sex is a risk factor for …