Multiple studies have investigated the association of interleukin-6 (IL-6) gene
polymorphisms and osteoarthritis (OA) risk, but failed to reach a consistent conclusion …

Observational and experimental studies have arrived at inconsistent conclusions about
whether common polymorphisms in IL-6, IL-1A, and IL-1B genes are associated with an …

Background Osteoarthritis (OA) is the most common form of human polyarthritis. Many
genetic factors have been implicated in OA. It was reported that a polymorphism in the gene …

OBJECTIVE: Interleukin-6 is a pro-inflammatory cytokine involved in the pathogenesis of
osteoarthritis (OA). We investigated the role of two single nucleotide polymorphisms (SNPs) …

Osteoarthritis (OA) is a complex disorder characterized by degenerative articular cartilage in
which inflammatory mechanisms play a major role in the pathogenesis. Interleukin-6 (IL6), a …

Abstract Purpose Interleukin 8 (IL-8), as a member of the CXC chemokine family, has a
regulatory role in joint inflammation and cartilage degradation, and contribute to the …

Osteoarthritis (OA) is the most prevalent disease of the musculoskeletal system and it has an
important genetic component. Despite several reports have shown the involvement of pro …

Objectives The association of interleukin-6 (IL-6)-174G/C (rs1800795) and IL-6-572G/C
(rs1800796) single-nucleotide polymorphism (SNP) with the risk of acquiring rheumatoid …

Background This case-control study aims to examine the association between the
Interleukin-6 (IL-6) rs12700386 polymorphism and the increased risk of developing …

Objective We performed a meta-analysis to determine the effect Interleukin-6 (IL-6) promoter
polymorphism (− 174 G> C,− 572 G> C, and− 597 G> A) have on the development …