Applying a 4D Multiscale In Vivo Tumor Growth Model to the Exploration of Radiotherapy Scheduling: The Effects of Weekend Treatment Gaps and P53 Gene Status …
DD Dionysiou, GS Stamatakos Jr - Cancer Informatics, 2006 - journals.sagepub.com
The present paper aims at demonstrating clinically oriented applications of the multiscale
four dimensional in vivo tumor growth simulation model previously developed by our …
four dimensional in vivo tumor growth simulation model previously developed by our …
A four-dimensional simulation model of tumour response to radiotherapy in vivo: parametric validation considering radiosensitivity, genetic profile and fractionation
The aim of this paper is to present the current state of a four-dimensional simulation model of
solid tumour growth and response to radiotherapy developed by our group. The most …
solid tumour growth and response to radiotherapy developed by our group. The most …
A spatio-temporal simulation model of the response of solid tumours to radiotherapy in vivo: parametric validation concerning oxygen enhancement ratio and cell cycle …
VP Antipas, GS Stamatakos… - Physics in Medicine …, 2004 - iopscience.iop.org
Advanced bio-simulation methods are expected to substantially improve radiotherapy
treatment planning. To this end a novel spatio-temporal patient-specific simulation model of …
treatment planning. To this end a novel spatio-temporal patient-specific simulation model of …
Towards predicting the response of a solid tumour to chemotherapy and radiotherapy treatments: clinical insights from a computational model
GG Powathil, DJA Adamson… - PLoS computational …, 2013 - journals.plos.org
In this paper we use a hybrid multiscale mathematical model that incorporates both
individual cell behaviour through the cell-cycle and the effects of the changing …
individual cell behaviour through the cell-cycle and the effects of the changing …
A four-dimensional computer simulation model of the in vivo response to radiotherapy of glioblastoma multiforme: studies on the effect of clonogenic cell density
GS Stamatakos, VP Antipas… - The British journal of …, 2006 - academic.oup.com
Tumours behave as complex, self-organizing, opportunistic dynamic systems. In an attempt
to better understand and describe the highly complicated tumour behaviour, a novel four …
to better understand and describe the highly complicated tumour behaviour, a novel four …
An advanced discrete state–discrete event multiscale simulation model of the response of a solid tumor to chemotherapy: Mimicking a clinical study
GS Stamatakos, EA Kolokotroni, DD Dionysiou… - Journal of theoretical …, 2010 - Elsevier
In this paper an advanced, clinically oriented multiscale cancer model of breast tumor
response to chemotherapy is presented. The paradigm of early breast cancer treated by …
response to chemotherapy is presented. The paradigm of early breast cancer treated by …
A Patient-specific in vivo Tumor and Normal Tissue Model for Prediction of the Response to Radiotherapy
VP Antipas, GS Stamatakos… - Methods of Information …, 2007 - thieme-connect.com
Objectives: Integration of multiscale experimental cancer biology through the development
of computer simulation models seems to be a necessary step towards the better …
of computer simulation models seems to be a necessary step towards the better …
A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies
Background Radiotherapy outcomes are usually predicted using the Linear Quadratic
model. However, this model does not integrate complex features of tumor growth, in …
model. However, this model does not integrate complex features of tumor growth, in …
Computer simulation and modelling of tumor spheroid growth and their relevance for optimization of fractionated radiotherapy.
W Duechting, W Ulmer, R Lehrig… - … und Onkologie: Organ …, 1992 - europepmc.org
As previous papers show, our group developed computer models simulating spatial (3D)
tumor growth of an in vitro tumor spheroid. These models were extended by implementing …
tumor growth of an in vitro tumor spheroid. These models were extended by implementing …
A patient-specific in vivo tumor and normal tissue model for prediction of the response to radiotherapy.
G Stamatakos, VP Antipas… - Methods of Information in …, 2007 - europepmc.org
Objectives Integration of multiscale experimental cancer biology through the development of
computer simulation models seems to be a necessary step towards the better understanding …
computer simulation models seems to be a necessary step towards the better understanding …