[HTML][HTML] Electrospun fiber-based micro-and nano-system for delivery of high concentrated quercetin to cancer cells

A Hudecki, I Rzeszutek, A Lewińska, T Warski… - Biomaterials …, 2023 - Elsevier
The anticancer potential of quercetin (Q), a plant-derived flavonoid, and underlining
molecular mechanisms are widely documented in cellular models in vitro. However …

A controlled release system for quercetin from biodegradable poly (lactide-co-glycolide)–polycaprolactone nanofibers and its in vitro antitumor activity

P Vashisth, RP Singh, V Pruthi - Journal of Bioactive and …, 2016 - journals.sagepub.com
Quercetin is a potent natural antioxidant but has limited therapeutic applications due to its
short half-life in body fluids. In order to improve the efficacy of quercetin and overcome its …

Antioxidant and antitumor activities of novel quercetin-loaded electrospun cellulose acetate/polyethylene glycol fibrous materials

N Stoyanova, M Spasova, N Manolova, I Rashkov… - Antioxidants, 2020 - mdpi.com
The aim of present study was to obtain novel fibrous materials based on cellulose derivative
and polyethylene glycol loaded with natural biologically active compound quercetin by …

Development of quercetin-loaded electrospun nanofibers through shellac coating on gelatin: Characterization, colon-targeted delivery, and anticancer activity

SF Li, TG Hu, H Wu - International Journal of Biological Macromolecules, 2024 - Elsevier
Quercetin possesses multiple biological activities. To achieve efficient colon-specific release
of quercetin, new composite nanofibers were developed by coating pH-responsive shellac …

Controlled Release of Curcumin and Hypocrellin A from Electrospun Poly(l-Lactic Acid)/Silk Fibroin Nanofibers for Enhanced Cancer Cell Inhibition

P Lin, H Gu, X Zhuang, F Wang, X Hu - ACS Applied Bio Materials, 2024 - ACS Publications
Nanofibers have emerged as a highly effective method for drug delivery, attributed to their
remarkable porosity and ability to regulate drug release rates while minimizing toxicity and …

Preparation and characterization of electrospun colon-specific delivery system for quercetin and its antiproliferative effect on cancer cells

P Wen, MH Zong, TG Hu, L Li, H Wu - Journal of agricultural and …, 2018 - ACS Publications
To improve the oral bioavailability of quercetin (Q) and achieve colon-specific release, a
core–sheath electrospun fiber mat containing Q-loaded chitosan nanoparticle (Q-loaded …

Quercetin functionalized hybrid electrospun nanofibers for wound dressing application

SK Karuppannan, MJH Dowlath, R Ramalingam… - Materials Science and …, 2022 - Elsevier
Quercetin is a potential phytochemical with high anti-inflammatory and antioxidant activities
known to treat numerous ailments. In this study, quercetin loaded polycaprolactone …

Polyphenol-loaded polycaprolactone nanofibers for effective growth inhibition of human cancer cells

YJ Kim, MR Park, MS Kim, OH Kwon - Materials Chemistry and Physics, 2012 - Elsevier
The use of polymeric nanofibers as drug carriers can be promising in the future for
biomedical applications, especially postoperative local chemotherapy. PCL is a …

Emblica officinalis-loaded poly (ε-caprolactone) electrospun nanofiber scaffold as potential antibacterial and anticancer deployable patch

GK Arbade, V Kumar, V Tripathi, A Menon… - New Journal of …, 2019 - pubs.rsc.org
Biological functions of nanofiber scaffolds can be engineered via the incorporation of plant
extracts. In the present study, Emblica officinalis (EO)(Indian Gooseberry known as amla) …

Dual drug release mechanisms through mesoporous silica nanoparticle/electrospun nanofiber for enhanced anticancer efficiency of curcumin

L Xu, W Li, S Sadeghi‐Soureh… - … Research Part A, 2022 - Wiley Online Library
Electrospun nanofibers (NFs)‐based drug delivery approaches are of particular interest as a
hopeful implantable nanoplatform for localized cancer therapy and treating tissue defect …