In silico evaluation of food‐derived carotenoids against SARS‐CoV‐2 drug targets: Crocin is a promising dietary supplement candidate for COVID‐19

S Mujwar, L Sun, O Fidan - Journal of Food Biochemistry, 2022 - Wiley Online Library
The current COVID‐19 pandemic is severely threatening public healthcare systems around
the globe. Some supporting therapies such as remdesivir, favipiravir, and ivermectin are still …

Antiviral activity of two marine carotenoids against SARS-CoV-2 virus entry in silico and in vitro

SK Yim, I Kim, B Warren, J Kim, K Jung… - International Journal of …, 2021 - mdpi.com
The marine carotenoids fucoxanthin and siphonaxanthin are powerful antioxidants that are
attracting focused attention to identify a variety of health benefits and industry applications …

Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations

SV Giofrè, E Napoli, N Iraci, A Speciale… - Computers in Biology …, 2021 - Elsevier
The outbreak of COVID-19 disease caused by SARS-CoV-2, along with the lack of targeted
medicaments, forced the scientific world to search for new antiviral formulations. In the …

Potential of Marine Terpenoids against SARS-CoV-2: An In Silico Drug Development Approach

A Sahoo, S Fuloria, SS Swain, SK Panda, M Sekar… - Biomedicines, 2021 - mdpi.com
In an emergency, drug repurposing is the best alternative option against newly emerged
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. However, several …

[HTML][HTML] Carotenoids: Therapeutic strategy in the battle against viral emerging diseases, COVID-19: An overview

A Khalil, D Tazeddinova, K Aljoumaa… - … nutrition and food …, 2021 - ncbi.nlm.nih.gov
Carotenoids, a group of phytochemicals, are naturally found in the Plant kingdom,
particularly in fruits, vegetables, and algae. There are more than 600 types of carotenoids …

[HTML][HTML] Berries anthocyanins as potential SARS-CoV–2 inhibitors targeting the viral attachment and replication; molecular docking simulation

O Messaoudi, H Gouzi, AN El-Hoshoudy… - Egyptian Journal of …, 2021 - Elsevier
The viral respiratory disease, severe acute respiratory syndrome (SARS), has turned into a
global health concern. Till now, there is no drug or vaccine has yet been specifically …

[HTML][HTML] In silico screening of potential anti–COVID-19 bioactive natural constituents from food sources by molecular docking

J Xu, L Gao, H Liang, S Chen - Nutrition, 2021 - Elsevier
Objective Through molecular docking of Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) 3CL hydrolytic enzyme (3CL pro) and angiotensin-converting enzyme Ⅱ …

Culinary spice bioactives as potential therapeutics against SARS-CoV-2: Computational investigation

J Natesh, P Mondal, D Penta, AAA Salam… - Computers in Biology …, 2021 - Elsevier
Abstract Background Coronavirus disease-2019 (COVID-19) is an infectious pandemic
caused by SARS-CoV-2. SARS-CoV-2 main protease (M pro) and spike protein are crucial …

Immunomodulatory and anti‐inflammatory potential of crocin in COVID‐19 treatment

M Ghasemnejad‐Berenji - Journal of Food Biochemistry, 2021 - Wiley Online Library
The current COVID‐19 pandemic is one of the most devastating events in recent history. In
the lack of a specific treatment and vaccine for this novel infection, finding effective drugs …

In silico identification of new anti-SARS-CoV-2 agents from bioactive phytocompounds targeting the viral spike glycoprotein and human TLR4

NC Das, RK Labala, R Patra… - Letters in Drug …, 2022 - ingentaconnect.com
Background: The recent outbreak of novel coronavirus disease (COVID-19) pandemic
caused by SARS-CoV-2 has posed a tremendous threat to mankind. The unavailability of a …