DNA methylation: a potential mediator between air pollution and metabolic syndrome

P Poursafa, Z Kamali, E Fraszczyk, HM Boezen… - Clinical …, 2022 - Springer
Given the global increase in air pollution and its crucial role in human health, as well as the
steep rise in prevalence of metabolic syndrome (MetS), a better understanding of the …

Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …

[HTML][HTML] Particulate matter exposure is associated with inflammatory gene methylation in obese subjects

L Cantone, S Iodice, L Tarantini, B Albetti… - Environmental …, 2017 - Elsevier
Background Overweight and obesity are becoming more widespread with alarming
projections for the coming years. Obesity may increase susceptibility to the adverse effects of …

Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA)

GC Chi, Y Liu, JW MacDonald, RG Barr… - Environmental …, 2016 - Springer
Background DNA methylation may mediate effects of air pollution on cardiovascular
disease. The association between long-term air pollution exposure and DNA methylation in …

From air pollution to cardiovascular diseases: the emerging role of epigenetics

MM Micheu, MV Birsan, R Szép, Á Keresztesi… - Molecular biology …, 2020 - Springer
The association between air pollution and a wide-ranging spectrum of acute and chronic
disorders—including cardiovascular diseases—is widely acknowledged. Exposure to …

The impact of air pollution on our epigenome: how far is the evidence?(A systematic review)

R Alfano, Z Herceg, TS Nawrot… - Current environmental …, 2018 - Springer
Abstract Purpose of Review This systematic review evaluated existing evidence linking air
pollution exposure in humans to major epigenetic mechanisms: DNA methylation …

Association between long-term air pollution exposure and DNA methylation: the REGICOR study

S Sayols-Baixeras, A Fernández-Sanlés… - Environmental …, 2019 - Elsevier
Introduction Limited evidence suggests that epigenetic mechanisms may partially mediate
the adverse effects of air pollution on health. Our aims were to identify new genomic loci …

Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

MK Lee, CJ Xu, MU Carnes, CE Nichols, JM Ward… - Clinical …, 2019 - Springer
Background Ambient air pollution is associated with numerous adverse health outcomes,
but the underlying mechanisms are not well understood; epigenetic effects including altered …

Particulate matter exposure shapes DNA methylation through the lifespan

L Ferrari, M Carugno, V Bollati - Clinical epigenetics, 2019 - Springer
Exposure to airborne particulate matter (PM) has been associated with detrimental health
effects. DNA methylation represents the most well-studied epigenetic factor among the …

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

EW Tobi, RC Slieker, R Luijk, KF Dekkers, AD Stein… - Science …, 2018 - science.org
Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation
(DNAm), underlie the relationship between adverse intrauterine conditions and adult …