The mammary gland is a unique tissue and the defining feature of the class Mammalia. It is a
late-evolving epidermal appendage that has the primary function of providing nutrition for …

Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Mammary gland development occurs through distinctive stages throughout embryonic and
pubertal development and reproductive life. At each stage, different signals are required to …

The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

Mammary gland development occurs over multiple phases, beginning in the mammalian
embryo and continuing throughout reproductive life. The remarkable morphogenetic …

Introduction The mammary primordium forms during embryogenesis as a result of inductive
interactions between its constitutive tissues, the mesenchyme and epithelium, and …

Understanding the complexity and heterogeneity of mammary cell subpopulations is vital to
delineate the mechanisms behind breast cancer development, progression and prevention …

The mammary gland develops through several distinct stages. The first transpires in the
embryo as the ectoderm forms a mammary line that resolves into placodes. Regulated by …

The mammary gland consists of cells with gene expression patterns reflecting their cellular
origins, function, and spatiotemporal context. However, knowledge of developmental …

Under normal conditions, the most significant expansion and differentiation of the adult
mammary gland occurs in response to systemic reproductive hormones during pregnancy …