Cisplatin is one of the extensively used anticancer drugs against various cancers. Dosage
dependent nephrotoxicity is the major problem in cisplatin chemotherapy. Cisplatin induced …

Clinical efficacy of the widely used anticancer drug cisplatin is limited due to its adverse side
effects in normal tissues mediated by oxidative stress. This study was aimed to investigate …

Objectives To investigate the protective effect of vanillin in cisplatin (CP)-induced
nephrotoxicity in rats and elucidate the role of nrf-2 and its downstream antioxidant …

This study aims to determine the potential protective effects of ferulic acid against cisplatin-
induced nephrotoxicity and to compare its effect with curcumin, a well-known protective …

A large number of natural products and dietary components have been evaluated as
potential chemoprotective agents. In the present investigation we report the effects of pre …

This study aimed to assess the protective effect of hesperidin (HES) and rutin (RUT) against
cisplatin‐induced nephrotoxicity in male rats. Cisplatin (5 mg/kg, intraperitoneal) caused …

Cisplatin (CDDP) is one of the first-line anticancer drugs; however, the major limitation of
CDDP therapy is development of nephrotoxicity (25–35% cases), whose precise mechanism …

The present study examined the effect of petroleum ether, ethyl acetate and alcoholic
extracts of aerial parts of Vernonia cinerea (500 mg/kg, po) on cisplatin-induced …

In this study, the antioxidant effect of aminoguanidine on nephrotoxicity of a single dose of
cisplatin is investigated and compared with the effects of well-known antioxidants vitamin C …

This study aimed to assess the protective effect of cinnamic acid (CA) and cinnamaldehyde
(CD) against cisplatin‐induced nephrotoxicity. A single dose of cisplatin (5 mg/kg), injected …