[HTML][HTML] Macrophages in pancreatitis: Mechanisms and therapeutic potential

F Hu, N Lou, J Jiao, F Guo, H Xiang, D Shang - Biomedicine & …, 2020 - Elsevier
Macrophages play a crucial role in the pathogenesis of pancreatitis that is a common
gastrointestinal disease. Particularly, macrophages differentiate into different phenotypes …

[HTML][HTML] Role of macrophages in the progression of acute pancreatitis

S Gea-Sorlí, D Closa - World journal of gastrointestinal …, 2010 - ncbi.nlm.nih.gov
In addition to pancreatic cells, other inflammatory cell populations contribute to the
generation of inflammatory mediators during acute pancreatitis. In particular, macrophages …

Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis

J Xue, V Sharma, MH Hsieh, A Chawla, R Murali… - Nature …, 2015 - nature.com
Chronic pancreatitis (CP) is a progressive and irreversible inflammatory and fibrotic disease
with no cure. Unlike acute pancreatitis (AP), we find that alternatively activated macrophages …

Inflammation in acute and chronic pancreatitis

A Habtezion - Current opinion in gastroenterology, 2015 - journals.lww.com
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology Log in or …

[HTML][HTML] Essential role of monocytes and macrophages in the progression of acute pancreatitis

P Shrivastava, M Bhatia - World journal of gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is an inflammatory condition of the pancreas caused by an
imbalance in factors involved in maintaining cellular homeostasis. Earliest events in AP …

Immune response mechanisms in acute and chronic pancreatitis: strategies for therapeutic intervention

J Glaubitz, S Asgarbeik, R Lange, H Mazloum… - Frontiers in …, 2023 - frontiersin.org
Acute pancreatitis (AP) is one of the most common inflammatory diseases of the
gastrointestinal tract and a steady rising diagnosis for inpatient hospitalization. About one in …

[HTML][HTML] The role of pancreatic infiltrating innate immune cells in acute pancreatitis

C Peng, Z Li, X Yu - International journal of medical sciences, 2021 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a leading cause of gastrointestinal-related hospital admissions
with significant morbidity and mortality. Although the underlying pathophysiology of AP is …

Immune cells and immune-based therapy in pancreatitis

J Xue, V Sharma, A Habtezion - Immunologic research, 2014 - Springer
Alcohol and gallstones are the most common etiologic factors in acute pancreatitis (AP).
Recurrent AP can lead to chronic pancreatitis (CP). Although the underlying …

Novel circulating and tissue monocytes as well as macrophages in pancreatitis and recovery

M Manohar, EK Jones, SJS Rubin, PB Subrahmanyam… - Gastroenterology, 2021 - Elsevier
Background And Aims Acute pancreatitis (AP) is an inflammatory disease with mild to severe
course that is associated with local and systemic complications and significant mortality …

[HTML][HTML] Pathogenic mechanisms of pancreatitis

M Manohar, AK Verma, SU Venkateshaiah… - World journal of …, 2017 - ncbi.nlm.nih.gov
Pancreatitis is inflammation of pancreas and caused by a number of factors including
pancreatic duct obstruction, alcoholism, and mutation in the cationic trypsinogen gene …