Abstract Pyrazolo [3, 4-d] pyrimidine ring system constitute an important class of heterocyclic
compounds which can serve as a promising scaffold exhibiting many pharmacological …

Abstract Pyrazolo [1, 5-a] pyrimidine scaffold is one of the privileged hetrocycles in drug
discovery. Its application as a buliding block for developing drug-like candidates has …

Abstract Pyrazolo [4, 3-d] pyrimidine, a fused heterocycle bearing pyrazole and pyrimidine
portions has gained a significant attention in the field of bioorganic and medicinal chemistry …

Being the pyrazolo [3, 4-d] pyrimidine ring system isoster with the adenine scaffold of ATP,
many synthetic approaches for the construction of this bicyclic system have been developed …

The development of new synthetic routes towards pyrazolo [1, 5-a] pyrimidines for their
biological and medicinal exploration is an attractive area for researchers. This review …

Abstract Thiazolo [4, 5-d] pyrimidines are fused heterocyclic ring-systems that can be viewed
at the first glance as purine isosteres. They are the 7 thia-analogs of purines via the …

Pyrazolopyrimidines are fused heterocyclic ring systems which structurally can consider as
bioisosteres of adenine, which is fundamental for every aspect of cell life. Pyrazolo [3, 4-d] …

Previously unknown N-3-substituted pyrido [1′, 2′: 1, 5] pyrazolo [3, 4-d] pyrimidine
derivatives were synthesized by a straightforward four-step synthesis. Starting from a 1 …

Among the various heterocyclic molecules employed for drug design and discovery,
pyrazolopyridine is one of the promising pharmacophores. Pyrazolopyridine is a result of …

Pyrimidine derivatives have played an important role in the chemistry of biological systems.
This review focuses on recent work of our studies on the synthesis and biological activity of …